Advances in 3D Printing and Cell Culture Technologies for Biomedical Applications

This annotated bibliography discusses recent advances in 3D printing of biomaterials and 3D cell culture technologies enabling tissue-like structures to be created in vitro. The authors examine the impact of 3D printing on maintainability and the development of cells in the lab to explore a particular natural element or process under various test conditions.

Annotated Bibliography and Recommendations
Reference 1
The 3D Printing guarantees to create complex biomedical gadgets as indicated by configuration
with the use of the computer by utilizing particular anatomical information. Since its use as pre-
surgical models for visualization and tooling, the 3D Printing has developed with time to make
gadgets that are unique, implants, tissue building, platforms for diagnostics, and medical
conveyance systems. The acceleration of this technology has been accelerated by the great
interest by the public which is coupled by the availability of 3D printers at affordable prices thus
creating and interests in regenerative medicine by combining stem cells with 3D scaffolds. Prior
to the use of 3D in the generation of cells, there are a number of challenges that require attention.
The article describes each of the 3D technologies merits as well as pointing out key limitations
that make ways for future research with a view to advancing the additive manufacturing. The
article is essential in giving the pros and cons of each technology that are related to 3D printing
technology.
The authors’ expertise are in biomedical engineering and they sought to examine advances in 3D
printing in relation to biomaterials.in their paper they talk about the impact of 3D printing on
maintainability regarding the development, plans of action, and the arrangement of significant
value chains.
This assist in getting the benefits that 3D technology has brought since it was incepted as well as
giving the demerits of the technology. It guides the researcher in getting to understand the deeper
part of 3D technology in the applications applied.
Reference 2
The investigation in mammals’ cell science frequently depends on creating in vitro models to
empower the development of cells in the lab to explore a particular natural component or process
under various test conditions. The nature of such models and how they speak to the conduct of
cells in genuine tissues assumes a basic part in the estimation of the information delivered as
well as how it is utilized. Lately, innovations have been produced to upgrade the manner in
which specialists can develop cells and all the more promptly make tissue‐like structures. The

article gives an analysis of the use of 2D as well as reviewing the same on the 3D tissue model
which can be scaffold either by the use of synthetic or natural tissues.
It points out that there are no specific means of making the tissue but researchers have to select
an appropriate method to use. It implies that tissue to mimic human organs is possible with the
correct choice of method and the use of right technology.
The 3D bioprinting may have other benefits that additionally have positive moral outcomes, for
instance, making contrasting options to organ testing, filling a therapeutic requirement for minors
and maintaining a distance from species of animals.
The authors’ are specialists in biomedical engineering and they sought to examine 3D cell
culture technologies in relation to tissue‐like structures in anatomy. They established that 3D bio-
printing has a great deal to offer throughout time should it move past a calculated treatment,
however, it is a zone that requires moral oversight and control.
The article is of great importance in getting to see the use of 3D technology in the creation of
human cells, tissues as well as bionic parts. It is going to solve various problems that human
being encounter in organ transplant.

References
1. Chia, H. N., & Wu, B. M. (2015). Recent advances in 3D printing of biomaterials. Journal of
biological engineering, 9(1), 4. Retrieved from
https://jbioleng.biomedcentral.com/articles/10.1186/s13036-015-0001-4
2. Knight, E., & Przyborski, S. (2015). Advances in 3D cell culture technologies enabling tissue‐
like structures to be created in vitro. Journal of anatomy, 227(6), 746-756. Retrieved from
https://onlinelibrary.wiley.com/doi/full/10.1111/joa.12257