This case study discusses the quality use of medicines for Ms. Tong, who is on medication for stomach ulcers caused by the bacterium, Helicobacter pylori. The study assesses Ms. Tong’s medication chart and identifies two significant risks associated with the use of these medicines. It also describes the strategies a nurse may implement to prevent/manage the risks identified. The study further identifies and describes one significant risk that each of the medications ibuprofen and St John’s wort may contribute to when used in combination with Ms. Tong’s currently prescribed medication. Lastly, the study identifies and explains three key points for education that will be provided to Ms. Tong in relation to the general use of over-the-counter medications prior to her discharge.