Neurovascular Pain Accompanied

Running Head: REPORT 0
BIOLOGY

REPORT 1
Abstract
Migraine is a syndrome which involves neurovascular pain accompanied with
changes in the processing of central neural. It involves the triggering of the
trigeminovascular system which cause the inflammation and painful sensation. Triptan is a
part of family of tryptamine drug used in the treatment of migraine headaches. They help in
broad spectrum headaches which involves immense discomfort and pain and involved with
the neurological tension. The drug binds to the receptors which are present in the blood
vessels, and the nerve ending in the brain. This results in inhibition of the pain and the
sensory inflammations. They have the affinity majorly for 1B and 1D receptor but not for
other receptors. Sumatriptan drug is usually administrated using four major ways namely
oral, subcutaneous method, intranasal and suppositories method. They are highly
contraindicated for the patients with already existing conditions of cardiovascular disease
such as hypertension, recent incident of stroke, coronary spasms, Raynaud’s disease and
other major conditions. Moreover, how the triptan medication and the basic drug affects the
receptors and relieves the pain. Regular and uninterrupted sleep is the key to prevent further
episodes as it relaxes the mind and washes away the unwanted stress and strain in the mind
and brain, which is one of the key factors for the delayed recovery. These treatments are well
approved and functional however, person must take several precautions to prevent the
condition by making modification in diet by having healthy and regular meals, regular
uninterrupted sleep, daily physical exercise or workouts and most importantly avoidance of
stressful work and scenarios.

REPORT 2
Contents
Abstract......................................................................................................................................1
Introduction................................................................................................................................3
Pathophysiology.........................................................................................................................3
Pharmacology.............................................................................................................................3
Drug naming...........................................................................................................................3
Pharmacodynamics.................................................................................................................3
Pharmacokinetics....................................................................................................................4
Route of Administration.........................................................................................................4
Precautions and Side Effects..................................................................................................4
Drug Interaction.........................................................................................................................5
Other interventions.....................................................................................................................5
Clinical practice.........................................................................................................................5
Conclusion..................................................................................................................................6
References..................................................................................................................................7