Adverse Drug Reactions in Hospital Inpatients: A Prospective Observational Study
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Added on 2023/05/28
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The paper aims to assess the severity, frequency and preventability of the hospital visits due to adverse drug reactions of a large tertiary care center. The paper also aimed to classify the visits due to the drug related problems and to identify the patient, prescriber, and the other factors related to this visit.
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Running head: RESEARCH METHODS RESEARCH METHODS Name of the Student Name of the university Author’s note
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1RESEARCH METHODS Adverse drug reactions Adverse drug reactions in hospital inpatients is one of the unfavorable occurrences in a hospital that might even lead to mortality and morbidity. Adverse drug reactions and is mainly caused due to drug misuse or multiple drug use. The paper aims to assess the severity, frequency and preventability of the hospital visits due to adverse drug reactions of a large tertiary care center. The paper also aimed to classify the visits due to the drug related problems and to identify the patient, prescriber, and the other factors related to this visit. The study design used for this study is a prospective observational design conducted at the emergency department of the Vancouver general hospital and a University of Columbia teaching hospital. Patients visiting the tertiary care center during the data collection shift were sampledsystematically.One patientfromallthe patientwasselectedby the helpof a computerized randomization program, who have presented in the 1 hour time period before the starting of the data collection shift. Other patients were again selected by randomization. The different outcome measures for this study selected are direct complaint of drug interaction,drugreactions,wrongselectionofthedrugssubtherapeuticdosagesandon adherence to the drugs. Descriptive statistics were used to analyses the data, consisting of the means, standard deviation, medians or the interquartile ranges.As per the results, adverse drug reaction was found to be 12 % of the emergency departmental visits. The rates of the hospital visits and hospital admissions were found to be longer that the patients visiting for other factors.
2RESEARCH METHODS The research paper has got several limitations. In spite of taking a standardized approach, bias might occur while determining whether the visit was a drug related visit. Again the physicians of the emergency department might be increased by the sudden attention to the drug related visits. One of the important limitation is the location chosen, which cannot be generalized to the entire population and thus the external validity is less. The internal validity of this paper is less as the as confounding was present than one of more variable.Due to the presence of the chance of bias, the study could not possibly eliminate the confounding factors. According to Brannen, (2017), the less is the chance of confounding, the higher is the internal validity of the result. Again, although an independent adjunction process was formulated for the review of the case summaries, but bias might also occur at this stage. Apart from reviewing the case summariesadjudicatorscouldgetaccesstoallthemedicalrecords.However,the recommendations put forward by this study is appropriate, that is future research should entirely emphasizeontheinterventionsforoptimizingthecommunicationbetweenthehealth professionals in acute care settings.
3RESEARCH METHODS References Brannen, J. (2017).Mixing methods: Qualitative and quantitative research. Routledge. Neuman, W. L. (2013).Social research methods: Qualitative and quantitative approaches. Pearson education.