The assignment aims to identify and characterize prohibitin-2 (PHB-2) as a receptor of Dengue virus in insect cells using CRISPR/Cas9 tools. The project involves cloning, transfection, and gene knockout techniques to silence the PHB-2 gene, resulting in mutation in the genomic sequence. The goal is to prove that PHB-2 is a receptor for Dengue virus and that silencing the gene can stop the virus from entering insect cells, ultimately controlling vector spreading.