Telomeres Protein Abstract: Structure, Function, and Cellular Role

This abstract provides a concise overview of telomeres and their associated proteins, focusing on their structure and function within the cell. The introduction highlights the role of telomerase in catalyzing the addition of telomeres to chromosome ends, emphasizing its importance in cell growth and the maintenance of DNA sequences. The main body delves into the structure and function of telomeres, including the repetitive nucleotide sequences, their role in protecting DNA, and their impact on cellular stability, especially in eukaryotic cells. The abstract also touches upon the structure of chromosomes and the role of telomeres in maintaining genetic information during DNA replication. The conclusion summarizes the key aspects of telomere structure and their significance in the context of DNA and cellular growth. The abstract is supported by multiple references to academic journals and books, which provide further details on the topic.

An abstract on the
Telomeres Protein

Table of Contents
INTRODUCTION...........................................................................................................................1
MAIN BODY...................................................................................................................................1
Discussing the CCrotein within the cell......................................................................................1
CONCLUSION ...............................................................................................................................2
REFERENCES................................................................................................................................3

INTRODUCTION
The telomerase ribonucleoprotine catalyse the additional of various new telomerase onto
chromosomes ends (Musgrove, Jansson and Stone, 2018). This include the growth of
mammalian cells and telomerase DNA that contains better growth and sequences of the six
nucleotides that repeat all over again (Bernal and Tusell 2018). All the structure and growth of
the telomerase. Various structure and growth of the telomerase include the growth and activities
of the catalysis.
MAIN BODY
Discussing the CCrotein within the cell
The structure and function that comprised the repeat sequence that is the bounding of
multiple telomeric that interacts with the proteins (Fernandes and et.al., 2020). This includes the
mammalian cells, telomere DNA that contains the double standard in the functions. Telomerase
contains the sequence of the six nucleotides that is repeated over again and again. This includes
all the repetition which makes them disposable somewhere. The functions protect the DNA, as
this can generally get less and shorter over the time passes. This does not impact any other loss
of the important information of the genetics (Shay, and Wright, 2019). The Telomerase is
required to maintain the chromosomes at the end and helps the chromosomes in the stability of
the eukaryotic cells. Telomerase helps in the loss of their non-coding DNA that is make available
in the erosions that generally happens during the DNA replication in every cell cycle. This is
important to protect the genetic information in the chromosomes (Luo and et.al., 2020).
Although, the basic structure of the chromosomes are in the structure that is located at the
internal nucleus of plant and animal cells. Every chromosomes is made by the help of protein
and contains the single molecule of the deoxyribonucleic acid that is generally known as DNA
(Pańczyszyn and et.al., 2020). This can be passed in between the parents to offspring. This DNA
generally contains some special recommendation that helps to make many types of the living
creature that will be unique and specific (Xu, 2018). Although, there are 2 telomerase present in
every chromosomes which is as equal to the 92 telomerase that is total number of 46
chromosomes. Generally, in young humans there are about 8,000 to 10,000 nucleotides present.
This can shorten with each cell divisions in the human body (Luo and et.al., 2020). However,
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this can reach to the critical length and stop the cells that helps to stop the dividing or dies of the
human beings.
CONCLUSION
From the above information it can be conclude that there are various structure and models
of the information that promote the DNA and growth in the telomerase. The critical aspect of the
business depends on the growth and enhancement of the DNA in the catalysis. This include
information about the structure follow by the DNA and catalysis of the business growth.
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REFERENCES
Books and Journals
Bernal, A. and Tusell, L., 2018. Telomeres: implications for cancer development. International
journal of molecular sciences, 19(1), p.294.
Fernandes, S.G., and et.al., 2020. Role of telomeres and Telomeric proteins in human
malignancies and their therapeutic potential. Cancers, 12(7), p.1901.
Higa, M., Fujita, M. and Yoshida, K., 2017. DNA replication origins and fork progression at
mammalian telomeres. Genes, 8(4), p.112.
Lim, C.J. and Cech, T.R., 2021. Shaping human telomeres: from shelterin and CST complexes to
telomeric chromatin organization. Nature Reviews Molecular Cell Biology, pp.1-16.
Luo, M., and et.al., 2020. Protection of telomeres 1 (POT1) of Pinus tabuliformis bound the
telomere ssDNA. Tree physiology, 40(1), pp.119-127.
Luo, M., and et.al., 2020. Single-stranded DNA-binding proteins in plant
telomeres. International Journal of Biological Macromolecules.
Luo, M., and et.al., 2020. Single-stranded DNA-binding proteins in plant
telomeres. International Journal of Biological Macromolecules.
Musgrove, C., Jansson, L.I. and Stone, M.D., 2018. New perspectives on telomerase RNA
structure and function. Wiley Interdisciplinary Reviews: RNA.9(2). p.e1456.
Pańczyszyn, A., and et.al., 2020. The role of telomeres and telomerase in the senescence of
postmitotic cells. DNA repair, p.102956.
Shay, J.W. and Wright, W.E., 2019. Telomeres and telomerase: three decades of progress.
Nature Reviews Genetics. 20(5). pp.299-309.
Shay, J.W. and Wright, W.E., 2019. Telomeres and telomerase: three decades of
progress. Nature Reviews Genetics, 20(5), pp.299-309.
Shay, J.W., 2018. Telomeres and aging. Current Opinion in Cell Biology, 52, pp.1-7.
Shoeb, M., and et.al., 2020. Telomeres in toxicology: Occupational health. Pharmacology &
Therapeutics, p.107742.
Smith, E.M., and et.al., 2020. Structural biology of telomeres and telomerase. Cellular and
Molecular Life Sciences, 77(1), pp.61-79.
Xu, Y., 2018. Recent progress in human telomere RNA structure and function. Bioorganic &
medicinal chemistry letters.28(15). pp.2577-2584.
Zhang, J.M., and et.al., 2019. Alternative lengthening of telomeres through two distinct break-
induced replication pathways. Cell reports, 26(4), pp.955-968.
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