An Abstract on Telomeres Protein: Structure, Function, and Genetics

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This abstract delves into the structure and function of telomeres and telomerase proteins within cells. It explores the role of telomeres in protecting DNA and maintaining chromosome stability in eukaryotic cells, discussing their shortening during cell division and the potential impact on genetic information. The abstract highlights the structure of chromosomes, composed of DNA and proteins, and their role in transmitting genetic information. It emphasizes the importance of telomerase in maintaining chromosome ends and preventing the loss of non-coding DNA. The abstract also references various academic journals, providing insights into the latest research on telomeres, including their role in diseases, G-quadruplexes, and the evolution of telomere sequences. The conclusion summarizes the importance of DNA growth and enhancement in the catalysis of telomeres protein.
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An abstract on the
Telomeres Protein
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Table of Contents
INTRODUCTION...........................................................................................................................1
MAIN BODY...................................................................................................................................1
Discussing the CCrotein within the cell......................................................................................1
CONCLUSION ...............................................................................................................................2
REFERENCES................................................................................................................................3
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INTRODUCTION
The telomerase ribonucleoprotine catalyse the additional of various new telomerase onto
chromosomes ends(Musgrove, Jansson and Stone, 2018). This include the growth of mammalian
cells and telomerase DNA that contains better growth and sequences of the six nucleotides that
repeat al over again. All the structure and growth of the telomerase. Various structure and growth
of the telomerase include the growth and activities of the catalysis.
MAIN BODY
Discussing the CCrotein within the cell.
The structure and function that comprised the repeat sequence that is the bounding of
multiple telomeric that interacts with the proteins. This includes the mammalian cells, telomere
DNA that contains the double standard in the functions. Telomerase contains the sequence of the
six nucleotides that is repeated over again and again. This includes all the repetition which makes
them disposable somewhere. The functions protect the DNA, as this can generally get less and
shorter over the time passes. This does not impact any other loss of the important information of
the genetics(Shay, and Wright, 2019). The Telomerase is required to maintain the chromosomes
at the end and helps the chromosomes in the stability of the eukaryotic cells. Telomerase helps in
the loss of their non-coding DNA that is make available in the erosions that generally happens
during the DNA replication in every cell cycle. This is important to protect the genetic
information in the chromosomes. Although, the basic structure of the chromosomes are in the
structure that is located at the internal nucleus of plant and animal cells. Every chromosomes is
made by the help of protein and contains the single molecule of the deoxyribonucleic acid that is
generally know as DNA. This can be passed in between the parents to offspring. This DNA
generally contains some special recommendation that helps to make many types of the living
creature that will be unique and specific(Xu, 2018). Although, there are 2 telomerase present in
every chromosomes which is as equal to the 92 telomerase that is total number of 46
chromosomes. Generally, in young humans there are about 8,000 to 10,000 nucleotides present.
This can shorten with each cell divisions in the human body. However, this can reach to the
critical length and stop the cells that helps to stop the dividing or dies of the human beings.
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CONCLUSION
From the above information it can be conclude that there are various structure and models
of the information that promote the DNA and growth in the telomerase. The critical aspect of the
business depend on the growth and enhancement of the DNA in the catalysis. This include
information about the structure follow by the DNA and catalysis of the business growth.
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REFERENCES
Books and Journals
Arish, N., Petukhov, D. and Wallach-Dayan, S.B., 2019. The role of telomerase and telomeres in
interstitial lung diseases: from molecules to clinical implications. International journal
of molecular sciences, 20(12), p.2996.
Bettin, N., Oss Pegorar, C. and Cusanelli, E., 2019. The emerging roles of TERRA in telomere
maintenance and genome stability. Cells, 8(3), p.246.
Boniewska-Bernacka, E., Pańczyszyn, A. and Cybulska, N., 2019. Telomeres as a molecular
marker of male infertility. Human Fertility, 22(2), pp.78-87.
Bryan, T.M., 2020. G-Quadruplexes at Telomeres: Friend or Foe?. Molecules, 25(16), p.3686.
Fathi, E., Charoudeh, H.N., Sanaat, Z. and Farahzadi, R., 2019. Telomere shortening as a
hallmark of stem cell senescence. Stem cell investigation, 6.
Mersaoui, S.Y. and Wellinger, R.J., 2019. Fine tuning the level of the Cdc13 telomere-capping
protein for maximal chromosome stability performance. Current genetics, 65(1),
pp.109-118.
Musgrove, C., Jansson, L.I. and Stone, M.D., 2018. New perspectives on telomerase RNA
structure and function. Wiley Interdisciplinary Reviews: RNA.9(2). p.e1456.
Pańczyszyn, A., Boniewska-Bernacka, E. and Goc, A., 2020. The role of telomeres and
telomerase in the senescence of postmitotic cells. DNA repair, p.102956.
Pasquier, E. and Wellinger, R.J., 2020. In vivo chromatin organization on native yeast telomeric
regions is independent of a cis-telomere loopback conformation. Epigenetics &
chromatin, 13, pp.1-22.
Peska, V. and Garcia, S., 2020. Origin, diversity, and evolution of telomere sequences in plants.
Frontiers in plant science, 11, p.117.
Recagni, M., Bidzinska, J., Zaffaroni, N. and Folini, M., 2020. The role of alternative
lengthening of telomeres mechanism in cancer: Translational and therapeutic
implications. Cancers, 12(4), p.949.
Saint-Leandre, B., Christopher, C. and Levine, M.T., 2020. Adaptive evolution of an essential
telomere protein restricts telomeric retrotransposons. Elife, 9, p.e60987.
Shay, J.W. and Wright, W.E., 2019. Telomeres and telomerase: three decades of progress.
Nature Reviews Genetics. 20(5). pp.299-309.
Sugarman, E.T., Zhang, G. and Shay, J.W., 2019. In perspective: An update on telomere
targeting in cancer. Molecular carcinogenesis, 58(9), pp.1581-1588.
Trybek, T., Kowalik, A., Góźdź, S. and Kowalska, A., 2020. Telomeres and telomerase in
oncogenesis. Oncology Letters, 20(2), pp.1015-1027.
Xu, Y., 2018. Recent progress in human telomere RNA structure and function. Bioorganic &
medicinal chemistry letters.28(15). pp.2577-2584.
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