Anopheles gambiae: Recent Findings and Control Measures

Running head: BROCHURE DOCUMENTS ON Anopheles gambiae
BROCHURE DOCUMENTS ON Anopheles gambiae
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1BROCHURE DOCUMENTS ON Anopheles gambiae
BROCHURE INFORMATION ON Anopheles gambiae
Topic
The brochure focuses on the causative agent of the African malaria (Anopheles gambiae).
It is considered as the most efficient vector of malaria in the Afrotropical region (CDC 2010). It
mainly composed of eight isolated reproductive species that cannot be distinguished
morphologically. This brochure will focus on some of the recent findings regarding Anopheles
gambiae aiming to reduce its ill effect.
Audience
The audience of this brochure is group of people who have been suffering from African
malaria or for the researchers who are keen to do research or gain knowledge about the recent
researches in this field.
The purpose of this brochure is to give an understanding on the current findings on
Anopheles gambiae, its host pathogen interaction in the midgut that is responsible for the
infection. The brochure would further provide the knowledge how the mosquitoes are gaining
resistance over the insecticides and the recent recommendations. It also provides an in depth
knowledge about the components of some natural essential oils containing repellant property and
also provides with the information regarding the tribal traditions of using herbs and plants to
prevent the vectors.

2BROCHURE DOCUMENTS ON Anopheles gambiae
Annotated Bibliography
Boissière, Anne, et al. "Midgut microbiota of the malaria mosquito vector Anopheles
gambiae and interactions with Plasmodium falciparum infection." PLoS pathogens 8.5
(2012): e1002742.
The vulnerability of the Anopheles mosquito to the plasmodium infections depends
mainly on the complex interaction between the vectors and the malarial parasite. a number of
studies have referred to the fact the mosquito poses an immunity to control the malarial
infection, but very little is known about the role of the environmental factors in the process of
transmission.
It has been found that it is the gut microbiota that is actually responsible for the mosquito
infection. A. gambiae mosquitoes were isolated from Cameroon and were experimentally
challenged with P. falciparum isolate and the bacterial content of the gut is subjected to
pyrosequencing analysis. On testing a broader richness was found in the gut microbiota. It was
found that during the development of the Plasmodium parasites in the mosquito vector, they
undergo complex phases. Parasite losses occur in the midgut of the mosquito where the immune
system actually comes in to play. In the genetic and the environmental factors that actually helps
in the infection.
The midgut microbiota of the adult mosquito contained five dominant phyla notably
Proteobacteria, Actinobacteria, Bacteroidetes, Fusobacteria, Firmicutes. It is after the blood
meal, when the parasites actually takes the advantage of the competitive interaction that takes
place between the bacteria for the nutrients and the host protection is overlooked by the bacteria
due to the competition. Although the gut microbiota helps in the homeostasis and protecting the