(BTE 483) - Anti-HIV Using Nanotechnology: Seminar Report on Innovative Approaches for HIV Treatment

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ANTI-HIV USING NANOTECHNOLOGY
BY
IGWE IFEOMA MODESTA
EBSU/2019/98309
A SEMINAR REPORT SUBMITTED TO THE DEPARTMENT OF
BIOTECHNOLOGY FACULTY OF BIOLOGICAL SCINECE, EBONYI STATE
UNIVERSITY, ABAKALIKI .
COURSE CODE: BTE 483
FEBRUARY, 2023

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ANTI-HIV USING NANOTECHNOLOGY
BY
IGWE IFEOMA MODESTA
EBSU/2019/98309
A SEMINAR REPORT SUBMITTED TO THE DEPARTMENT OF
BIOTECHNOLOGY FACULTY OF BIOLOGICAL SCINECE, EBONYI STATE
UNIVERSITY, ABAKALIKI .
IN PARTIAL FULFILLMENT OF THE REQUIREMENTS FOR THE AWARD OF
BACHELOR OF SCIENCE ( B. Sc.)
DEGREE IN BIOTECHNOLOGY
COURSE CODE: BTE 483
SUPERVISOR: PROF. E. I. UGWUJA
FEBRUARY, 2023

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APPROVAL
This seminar report titled Anti-HIV Using Nanotechnology carried out by Igwe Ifeoma
Modesta with the registration number EBSU/2019/98309 and presented to the Department of
Biotechnology, Faculty of Science, Ebonyi State University Abakaliki.
______________________ ____________________
PROF. E. I. UGWUJA Date
Seminar Supervisor
______________________ ____________________
DR. ALI. FEDRICK Date
Seminar Coordinator
______________________ ____________________
PROF. E. I. UGWUJA Date
Head of department

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CERTIFICATION
This is to certify that the seminar report titled Anti-HIV Using Nanotechnology carried out
by Igwe Ifeoma Modesta with the registration number EBSU/2019/98309 and presented to
the Department of Biotechnology, Faculty of Science, Ebonyi State University Abakaliki.
______________________ ____________________
PROF. E. I. UGWUJA Date
Seminar Supervisor
______________________ ____________________
DR. ALI. FEDRICK Date
Seminar Coordinator
______________________ ____________________
PROF. E. I. UGWUJA Date
Head of department

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ACKNOWLEDGEMENT
I wish to register my profound gratitude to god almighty for the guidance and Grace
throughout my life.
I'm grateful to the entire staff of Biotechnology department for making my learning
interesting educative and Worthwhile.
My special gratitude to my HOD Prof. E. I. Ugwuja for his effort to see that this works or the
light of the day. I appreciate all my amazing lecturers in the department, my wonderful
supervisor, prof. I. E. Ugwuja for his seasoned lectures, to them all, I say we bless Amen.
My regards to my amazing parents Mr and Mrs Francis Igwe, my guidance Mr and Mrs
Chigozie who financially supported my education pursuit, I said amen blessed by God
Almighty and to my beloved siblings, love you all, you are the best.

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Table of contents
Title page i
Approval ii
Acknowledgment iii
Table of content iv
Abstract v
CHAPTER ONE: INTRODUCTION
1.1 Background of the Study 1
CHAPTER TWO: DISCUSSIONS
2.1 Edification of Nanotechnology In Field Of Drug Delivery 6
2.2 Liposomes 7
2.3 Liposomal ARV Drug Formulation For Anti-HIV Effect 8
2.4 Dendrimer 9
2.4.1 Dendrimer formulation for targeting HIV-AIDS 10
2.4.2 FDA approved dendrimer of AIDS 11
2.5 Nanoparticle 12
2.5.1 Polymeric nanoparticles 12
2.5.2 Solid lipid nanoparticles (SLN) 12
2.5.3 Nano-structured lipid carries (NCL) 13
2.5.4 Inorganic nanoparticles 14
2.6 Polymeric Micelles 14
2.7 Nanocrystal 15
CHAPTER THREE: CONCLUSION
4.1 Conclusion 16
REFERENCE 17