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Assignment On Pathophysiology of STI

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Added on  2020-04-01

Assignment On Pathophysiology of STI

   Added on 2020-04-01

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Running Head: STISTIName of the StudentName of the University Author Note
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1STIIntroductionThe paper deals with the case study of Justin. On placement in a student’s health clinic ata local university, a 24 year old male student, named Justin is presented. He notices someworrying symptoms including blisters on his penis. The patient has not experienced thesesymptoms in the past. Upon investigation, the client revealed that the he had sex – including oralsex three times in last 24 hours. The patient reported that he had not used condoms as his partnerinformed him that the STD screen was clean for everything. In response to the case study, theassignment discusses the sexually transmitted infection (STI) that Justin is highly likely to suffer.In the context of the STI chosen the assignment will address the pathophysiology of this STI,theassessment and management of this STI, ethico-legal issues that may arise with the diagnosis ofan STI. Further, the assignment will discuss the role of the sexual health team members involvedin the management of Justin. Lastly, the education needs for Justin to prevent further STIs areoutlined. STI Justin has been practicing unsafe sex and is experimenting with his sexuality. Because ofhis unsafe sex practices, he is at risk of developing Genital herpes. It is one of the most commonSTIs. Pathophysiology of this STI Genital herpes is caused by the Herpes simplex virus (HSV) and in most cases HSV type2 is responsible for the disease. HSV-1 is often the cause of fever blisters or cold sores (Garland& Steben, 2014). However, the patient denies the history of cold sores on his mouth or sore
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2STIaround his genitals before. His case history highlights that he rarely practices the safe sex, thusthe blisters on penis in such situations is mainly caused by the genital herpes. Genital herpes iseasily transmitted through sexual contact and may happen even if the concerned person iscontaining virus without exhibiting the related signs or symptoms (Schiffer & Corey,2014). Asthe virus enters the skin it travels along the nerve path, where it can become dormant and persistthere indefinitely. Both HSV 1 and HSV 2 infections occur by contacting the infectitioussecretions on oral, anal and genital mucosal surfaces. Contacting other anatomical site such aseyes, non-mucosal surfaces, such as lesions on the buttocks and trunk can also cause genitalherpes. In this type of viral infection, the symptoms may appear months after the initial exposure.The mucous membrane lines the opening of the body, which is the door to the viruses. Theprimary infection is characterised with the small blisters on genital areas that may burst to leaveopen sores. Genital herpes mainly affect genitals, mouth, and anal region (Johnston & Corey,2016). Assessment and management of this STIDiagnosis of genital herpes includes several tests. PCR blood tests are used to look forpieces of viral DNA. This is most common test and is accurate. The health care providers maycollect sample from sores for cell culture and can be observed under microscope for HSV (Liu etal., 2015). Both the tests have a chance of giving false results, if the patient has started to recoverrecently. Antibodies against HSV do not show up until several weeks and it is difficult toidentify the time of exposure or noticeable exposure. With the help of the direct fluorescentantibody testing, it is easy to detect the glowing antibodies that stick to the viral antigens in thesample. This testing is useful to differentiate between the HSV 1 and HSV 2. Overall, the clinicaldiagnosis has low sensitivity and specificity (LeGoff et al. 2014).
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3STINurses can asses for impaired skin integrity that is related to skin inflammation, vesiclesand crusting. Further assessments include hyperthermia indicating increased hypothalamic setpoint, fatigue due to decrease in energy source and risk of imbalanced nutrition pertaining toappetite down and lastly acute pain that may be caused by the infection in pain neurons. Basedon the assessment HSV is diagnosed (Posavad e al., 2017). According to Fife et al. (2015), daily suppressive treatment with valaciclovir can reduceHSV-2transmission. This drug was investigated among HSV-2 discordant heterosexual couples.The infection was reduced by 75%, for clinical disease and reduces the acquisition (measured byserology) by 48%. Development of vaccine effective against this disease is not been found.Antiviral treatment is helpful and commonly prescribed medication include- Zovirax, Famvir,Valtrex, which are known to prevent outbreak. Antiviral medicine should be taken daily and itmakes the living easier. These medicines can be taken as pill. According to the guidelines ofWHO for adolescents with a first clinical episode of genital HSV infection, a standard dose ofaciclovir over valaciclovir or famciclovir is recommended (Sands-Lincoln & Goldmann, 2016).The dosages are as follows-aciclovir 400 mg orally thrice daily for 10 days aciclovir 200 mg orally five times daily for 10 days valaciclovir 500 mg orally twice daily for 10 days famciclovir 250 mg orally thrice daily for 10 daysIntermittent therapy can consist of antiviral therapy for five or ten days. Suppressivetreatment for recurrent infections includes taking the antiviral drugs everyday and is given for sixoutbreaks a year (Bibbins-Domingo et al., 2016). Therefore, the dosage may be like-
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