Assignment on Public Health Toxicology

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Added on 2020-04-21

Assignment on Public Health Toxicology

Added on 2020-04-21

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Running head: TOXICOLOGYToxicologyName of the StudentName of the UniversityAuthor Note

Assignment on Public Health Toxicology_1

1 TOXICOLOGYTable of ContentsIntroduction................................................................................................................................2Answer: 1...................................................................................................................................2Cell culture or Tissue culture.................................................................................................3Animal Model or Xenograft Model.......................................................................................3Computer Stimulations Model...............................................................................................4Answer: 2...................................................................................................................................6Answer: 3...................................................................................................................................6References..................................................................................................................................8

Assignment on Public Health Toxicology_2

2 TOXICOLOGYIntroductionAccording to the latest research published in Chemie International Edition by University of Warwick, there is new drug that is capable of manipulating body's natural signalling and the energy systems. This enables the body to attack the potent cancerous cells. They named the Drug ZL105 that has been derived from iridium metal (Romero-Canelón & Sadler, 2013; Hearn et al. 2013). Preliminary data indicates that the novel drug may be 10 times more potent than the other available anti-cancerous drugs in treating colon, ovarian, melanoma, breast and renal cancers (Habtemariam et al. 2016).(Source: Bole, 2017)Answer: 1Animal studies and cell cultures are two of the most crucial steps in determining the pahrmacodynamics, efficacy and mechanism of action of novel anti-cancerous drugs. High degree of genetic instability along with phenotypic variability is the characteristics of the heterogeneous population of timorous cells. Interaction between the host environment and tumor cells cause activation of the endothelial cells and fibroblasts, which is followed by the subsequent recruitment of the immune cells and inflammatory cells. The microenvironment, which is now modified, selects and subsequently modifies the phenotypic and genetic nature

Assignment on Public Health Toxicology_3

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Assignment on Public Health Toxicology