Assignment on Public Health Toxicology

Added on - 21 Apr 2020

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Running head: TOXICOLOGYToxicologyName of the StudentName of the UniversityAuthor Note
1TOXICOLOGYTable of ContentsIntroduction................................................................................................................................2Answer: 1...................................................................................................................................2Cell culture or Tissue culture.................................................................................................3Animal Model or Xenograft Model.......................................................................................3Computer Stimulations Model...............................................................................................4Answer: 2...................................................................................................................................6Answer: 3...................................................................................................................................6References..................................................................................................................................8
2TOXICOLOGYIntroductionAccording to the latest research published in Chemie International Edition byUniversity of Warwick, there is new drug that is capable of manipulating body's naturalsignalling and the energy systems. This enables the body to attack the potent cancerous cells.They named theDrug ZL105that has been derived from iridium metal (Romero-Canelón &Sadler, 2013;Hearn et al. 2013).Preliminary data indicates that the novel drug may be 10times more potent than the other available anti-cancerous drugs in treating colon, ovarian,melanoma, breast and renal cancers (Habtemariam et al. 2016).(Source: Bole, 2017)Answer: 1Animal studies and cell cultures are two of the most crucial steps in determining thepahrmacodynamics, efficacy and mechanism of action of novel anti-cancerous drugs. Highdegree of genetic instability along with phenotypic variability is the characteristics of theheterogeneous population of timorous cells. Interaction between the host environment andtumor cells cause activation of the endothelial cells and fibroblasts, which is followed by thesubsequent recruitment of the immune cells and inflammatory cells. The microenvironment,which is now modified, selects and subsequently modifies the phenotypic and genetic nature
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