promotion of the growth of uterine leiomyomas tumors (McKay, 2012). This is a proof that has
been developed through clinical and laboratory experiments.
Risk factors associated with uterine leiomyomas
Age: An increase in age is a promoter of uterine leiomyomas especially during the
reproductive years of an individual. The increase is found, through studies, to be rapid among
women when they are in the age bracket of the forties (David R. Gambling, 2013). This increase in
prevalence can be associated with increased growth of already existing fibroids besides an
increased willingness of women in the later reproductive years to undergo gynecologic surgery.
Obesity: Studies that show a strong correlation between obesity and the prevalence of
uterine leiomyomas. The correlation is such that for every 10-kg increase in the weight of an
individual, there is an estimated 21% increase in the risk. This applied to the body mass index as
well. An increase in the adult BMI corresponds to an increased uterine leiomyomas risk besides
an associated risk of gain in weight. The correlation between uterine leiomyomas risk and
obesity can be linked to the hormonal factors which are associated with obesity. Still, other
pathologic factors can as well be involved in this course (Lee, 2012). The conversion of adrenal
androgens to estrogen with the help of adipose tissue is a major hormonal activity that increases
the risk factor for uterine leiomyomas (David R. Gambling, 2013). More unbound and
physiologically active estrogen is produced as a result of the hepatic production of sex hormones.
Menopause: The absence of stimulations of the hormones due to menopause increases the
risks of uterine leiomyomas (Lombardi, 2012). Uterine leiomyomas among postmenopausal

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