1BIOLOGY Epinephrine is a hormone, which is secreted by the adrenal medulla, which functions to increase the cardiac output and increase blood glucose levels. This hormone is mainly released during acute stress conditions. Epinephrine has been found to act on all body tissues which varies by tissue types and expression of adrenergic receptors. Epinephrine has been found to control the contraction and relaxation of smooth muscles which are in turn controlled through epinephrine receptors (Deeney et al., 2018). Contraction of the muscles occurs by the binding of calmodulin to calcium ions. Binding of epinephrine to the receptors has been found to activate adenylate cyclase to produce cyclic AMP from ATP. This process, in turn, leads to the phosphorylation of MLCK which helps in the relaxing of smooth muscle tissues. Due to this physiological function associated with the attachment of epinephrine to the receptors, it has been used for asthma, cardiac arrests and anaphylactic shocks. Changes in functions associated with the liver have been found to be connected to the binding of epinephrine to the receptors. When epinephrine binds to the receptor outside lover cell, a conformational change occurs. The change in the receptor shape causes G protein to bind and get activated. Finally, the same process associated with breaking down of ATP to AMP in the presence of adenylate cyclase occurs glycogen is further broken down to glucose (Baynes, 2018). Thus. From the above discussion, it can be stated that epinephrine performs various physiological functions associated with receptors.
2BIOLOGY References Baynes,J.W.(2018).BiosynthesisandStorageofCarbohydrateinLiverand Muscle.Medical Biochemistry E-Book, 147. Deeney, B., Cao, G., Himes, B. E., Orfanos, S., & Panettieri, R. A. (2018). Epinephrine Induces Human Airway Smooth Muscle Contraction Through the Alpha-1 Adrenergic ReceptorAfterBeta-2AdrenergicReceptorDesensitization.InA29.NOVEL MECHANISMSFORAIRWAYSMOOTHMUSCLECONTRACTIONAND RELAXATION: POTENTIAL TARGETS FOR MODULATION(pp. A1218-A1218). American Thoracic Society.