The Brexit vote has created uncertainties, opportunities, and challenges for UK international businesses. The loss of free access to the European single market means additional costs and administrative bureaucracies. UK economic performance has declined, and businesses face difficulties in forging new market arrangements and penetrating new markets. The business environment is influenced by economic, legal, cultural, economic, and market forces. Politics, market forces, regulatory frameworks, and culture play important roles in the business environment. The impact of Brexit on UK international businesses includes loss of revenue, jobs, and trade partnerships, as well as increased costs and legal requirements. However, Brexit also inspires new trade policies and newer markets.