The assignment content discusses issues related to Microsoft Office 2016 files opening as read-only unexpectedly, with solutions provided for troubleshooting and editing documents. It also covers the importance of knowing one's audience and purpose when designing a document, as well as the factors that influence design, such as cognitive capacity and strategic thinking. The content further explores case studies involving Lucy and Mark, who use different business equipment and software to design presentations. Additionally, it touches on the importance of clarifying the target audience and purpose before designing a document.