1CASE STUDY ANALYSIS Introduction: This paper intends to critically analyse the provided case study and make use of the evidence base to propose recommendations that could improve the overall health outcome of the patient. Assessment: The general physical assessment of the patient states that patient weighs around 216.2 lbs and the height of the patient is documented to be 68”. The vital assessment of the patient states that his blood pressure is elevated and has been documented to be 164/79. Further, the respiratory rate is recorded to be 18, the heart rate has been reported to be 79 and the oxygen saturation has been documented to be 97%. The body temperature of the patient has been documented to be 97.1̊F. The general assessment of the patient reveals that the patient is normotensive and is devoid of any acute stress. The head to toes assessment states that that head is devoid of any lesions and is normocephalic in appearance. PERRLA, EOM are reported to be intact while assessing the eyes. Ear assessment suggest EAC’s are clear and the TM’s are normal. Nose assessment reveals that mucosa is normal. Throat assessment has also been reported to be clear with no presence of lesions or exudates. Neck assessment suggests no presence of masses or bruits. Chest assessment reveals clear lungs with no rales, rhonchi or wheezes. Heart assessment suggests normal respiratory rate devoid of murmurs, rubs or gallops. Bilateral LE edema in 1+ ankle has been reported. Abdominal assessment revealed soft, mild tenderness in the RUQ on palpating. Bowel sound was reported to be normal. Assessment of the extremities reported amputation of the left toe and approximate 1x1 cm left ball of foot stage 2 ulcer. No sign of discharge or infection was noticed. Skin assessment suggested no presence of rashes or lesions and physiological assessment suggested no localizing findings.
2CASE STUDY ANALYSIS Diagnosis: The case study reports symptoms that include significant weight gain within one year up to 20+ pounds, frequent urination, experiencing numbness in feet and stress.In addition to this, the previous medical history also suggested slow healing of a spider bite 10 years ago on the left leg in the anterior tibialis region and a toe blister which advanced to sepsis and MRSAosteomyelitisthateventuallyhadtobeamputated.Thepatientalsoreports experiencing intermittent vertigo, intermittent RUQ pain, experiencing pain accompanied with inflammation of the joints. The clinical investigation reports Glucose level to be 146, LDL to be 71, LDL/HDL Ratio to be 2.09 and triglyceride level to be 78. Upon considering the presenting symptoms, the previous medical history of the patient and comparing it with the clinical investigation results, the diagnosis for Diabetes can be confirmed. The evidence base suggests that the normal level of glucose in the blood during fasting should be less than 100 mg/dL. The amount of blood glucose equivalent to or higher than 126 mg/dL is treated as elevated and confirms the diagnosis of Diabetes (American Diabetes Association, 2018). In addition to this, the evidence base suggests that elevation of Glucose level in blood interferes with the normal wound healing process. Also, the symptoms of frequent urination, hypertension, weight gain is directly associated with the diagnosis of Diabetes (Zaccardi et al., 2016; Baynes, 2015). Evaluation of current Pharmacologic Therapy: The current prescribed medications include, Novolin N 100 unit.ml suspension 25 units BID, Novolin R 100 unit/ml subcu solution 25 units BID-TID meals and Bactrim DS 800/160 mg, 1 tab BID. The case scenario suggests that the patient had been under the prescribed medication for the previous 20 years but the blood glucose level of the patient has
3CASE STUDY ANALYSIS not been under control. The rationale for the prescription of Bactrim DS 800/160 mg can be explained as prevention from the probability of a bacterial infection. Evaluation of Possible Current Drug Interactions: The evidence base suggests that Novolin R acts as a potential hazard that could lead to renal dysfunction. Research studies mention that the requirement for Insulin could potentially be diminished in patients who have a previous medical history or hepatic or renal impairment (Drugs.com, 2019). The plausible cause for the same can be explained as poor glucose metabolism and reduced mechanism ability to carry out gluconeogenesis. Research studies also mention possible disease interaction triggering episodes adrenal insufficiency and autonomic neuropathy (Drugs.com, 2019). Plan: Additional Pharmacologic Therapy Required: Additional pharmacological therapy would comprise of prescribing Carvedilol for the management of elevated blood pressure. Carvedilol is basically the combined formulation of alpha /beta blocker and acts on the heart to reduce the blood pressure (Carvedilol, 2019). The prescribed medication dose would include 3.125 mg twice daily for 2 weeks and the patient would be advised to consume the drug with food so as to slow down the absorption of the drug (Carvedilol, 2019). If the prescribed dose is tolerated well by the patient, the dose could be increased to 6.25mg twice daily (Carvedilol, 2019). However, prior to initiating the drug, the patient must be asked to reduce fluid retention. The rationale for the prescription of the drug can be explained as its effect on reducing the blood pressure and no adverse drug interaction with Novolin N and Novolin R. In addition to this the dose of Novolin R could be changed to regular U-500 instead of 100 units/ml as it exhibits a longer duration of action (Drugs.com, 2019).
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4CASE STUDY ANALYSIS Interactions of proposed additional therapies: The prescribed medication are safe to be administered together and do not elicit adverse drug interaction or any potential side effects as informed by the evidence base (Drugs.com, 2019). Recommendations for non-pharmacologic therapies: Non-pharmacological therapies would include, training the patient self-management strategies to control symptoms and make lifestyle changes such as diet management to control the blood glucose level. In addition to this, other non-pharmacological intervention would include training the patient to monitor his blood glucose level by using the glucometer strips (De Boer et al., 2017). Referrals: In ordertoensuresymptomsmanagementthepatientwould bereferredtoa nutritionist and a physical trainer. The rationale for the referral can be explained as weight management which would directly help to control blood glucose level and elevated blood pressure level (Gabb et al., 2016). Other referral would include organising a referral to a psychotherapist in order to alleviate the symptoms of stress. Additional testing: Referral to additional testing would include conducting a mental state evaluation assessment for devising an appropriate intervention for stress and conducting a nutritional assessment for developing an appropriate diet plan to optimise the blood glucose level (American Diabetes Association, 2018). Education/Counselling:
5CASE STUDY ANALYSIS The patient would be educated about Diabetes and the lifestyle risk factors that result in elevation of the blood glucose level (Reusch & Manson, 2017). In addition to this, the patient would be made aware about the medication chart so as to ensure that the patient does not skip medications as it would deteriorate the physiological effect of the symptoms.
6CASE STUDY ANALYSIS Recommendations for follow up: Recommendations for follow up would include evaluation of the body weight for six months after implementing lifestyle changes such as making diet changes and adhering to exercise routine (Reusch & Manson, 2017). In addition to this, the patient would also be provided a medication log book which would be evaluated during the follow up which would help to track whether the patient has consumed the medications regularly (Gabb et al., 2016).
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7CASE STUDY ANALYSIS References: American Diabetes Association. (2018). 4. Lifestyle management: standards of medical care in diabetes—2018.Diabetes Care,41(Supplement 1), S38-S50. Baynes,H.W.(2015).Classification,pathophysiology,diagnosisandmanagementof diabetes mellitus.J diabetes metab,6(5), 1-9. carvedilol, G. (2019).Coreg (Carvedilol): Side Effects, Interactions, Warning, Dosage & Uses.[online]RxList.Availableat:https://www.rxlist.com/coreg- drug.htm#indications [Accessed 2 Aug. 2019]. De Boer, I. H., Bangalore, S., Benetos, A., Davis, A. M., Michos, E. D., Muntner, P., ... & Bakris, G. (2017). Diabetes and hypertension: a position statement by the American Diabetes Association.Diabetes Care,40(9), 1273-1284. Drugs.com(2019).NovolinRDiseaseInteractions-Drugs.com.[online]Drugs.com. Availableat:https://www.drugs.com/disease-interactions/insulin-regular,novolin- r.html#hypoglycemia [Accessed 2 Aug. 2019]. Gabb, G. M., Mangoni, A. A., Anderson, C. S., Cowley, D., Dowden, J. S., Golledge, J., ... & Schlaich, M. (2016). Guideline for the diagnosis and management of hypertension in adults—2016.Medical Journal of Australia,205(2), 85-89. Reusch, J. E., & Manson, J. E. (2017). Management of type 2 diabetes in 2017: getting to goal.Jama,317(10), 1015-1016. Zaccardi, F., Webb, D. R., Yates, T., & Davies, M. J. (2016). Pathophysiology of type 1 and type2diabetesmellitus:a90-yearperspective.Postgraduatemedical journal,92(1084), 63-69.