CASE STUDY
Discussion
In the case study the patient has a previous reported case of IBD. The clinical
presentation of IBD includes passage of pus or mucus, bloody diarrhoea and abdominal pain
(Loddo & Romano, 2015). In the case study, the 33-year old man was diagnosed with UC 4
years before and was present to the primary healthcare physicians with chronic diarrhoea,
extreme weight loss and anaemia arising from iron-deficiency. The thrombotic occlusion during
pulmonary embolism (PE) mainly occurs due to the development of deep vein thrombosis
(DVT). DVT is defined as the formation of blood clot in more than one deep vein. The
formations of progressive clots results in clot to break loose from the walls of the veins. The clot
then travels through the blood stream of the veins and lodge in the lungs resulting in the
development of PE. This is the reason why PE is popularly known as pulmonary
thromboembolism (Piazza, Hohlfelder & Goldhaber, 2015). The clotting in the lungs might be
responsible for symptoms displayed by the 33-year old man in the case study like pain in right
chest, increase in pain during inspiration while lying down.
Chung Lin, Hsu and Kao (2015) reported that IBD related with the chronic inflammation
might increase the vulnerability of developing PE and DVT however, there are poor
epidemiological evidences suggesting their relationships. Thus in order to address this concern,
Chung Lin, Hsu and Kao (2015) conducted a longitudinal nationwide cohort study in the Taiwan
healthcare field. The analysis of the results showed that the risk of DVT and PE are significantly
higher in the population that is suffering from IBD for a prolong period of time in comparison to
the general population. The underlying pathophysiology for this is highlighted as follows. Chung
Lin, Hsu and Kao (2015) are of the opinion that basic mechanism of thromboembolism includes
formation of hypercoagulability along with generation of endothelial dysfunction as represented

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Role of Inflammatory Bowel Disease in Pulmonary Embolism

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