Case Study Table of Contents Question

Case Study

Table of Contents
Question 1................................................................................................................. 3
Question 2................................................................................................................. 3
Question 3.................................................................................................................. 4
Question 4:................................................................................................................. 5
Question 5:................................................................................................................. 5
Question 6:................................................................................................................. 6

Question 1
1.1 Inflammation in the conjunctiva of eyes caused by bacteria or virus is called infectious
conjunctivitis. The most noticeable symptoms of infectious conjunctivitis is redness of eyes,
pain, and purulent release from eyes (Haddrill, 2019).
1.2 Of the listed four microorganisms Staphylococcus aureus bacteria is more likely to be the
cause of John’s eye infection. Because purulent discharge, pain are the signs of conjunctivitis by
Staphylococcus aureus.
 Legionella pneumophila: no, this bacterium is not responsible for conjunctivitis. It is the
causative agent of pneumonia and lung infection (Rathore, 2018).
 Plasmodium ovale: no, it is a kind of protozoa and it is responsible for non-falciparum
malaria (Okafor & Finnigan, 2019).
 Adenovirus: though adenovirus is a causative agent of conjunctivitis but in this case
study adenovirus is not the reason for it, because, doctor prescribes gentamicin which is a
drug used to stop the bacterial growth (Okafor & Finnigan, 2019).
 Staphylococcus aureus: This bacterium is supposed to be the causative agent of infectious
conjunctivitis to John. The signs and symptoms are similar to the Staphylococcus
infection. Also, doctor prescribes gentamicin that acts on bacteria (Bush, 2019).
Question 2
2.1 Gentamicin belongs to amino glycoside class of antibiotic used to inhibit the growth of
bacteria. It acts on necessary protein that bacteria use for their survival. Gentamicin binds with
ribosomal 30s subunits of bacteria which results inhibition of necessary protein synthesis. When
the drug binds with 16s rRNA of 30s ribosomal subunit, it leads to incorrect aminoacyl tRNA
bindings with mTNA codon site (Woodley et al., 2017). As a result, unstable complex
formation is observed between tRNA and elongation factor. Thus occuring of incorrect protein
formation is happened which may cause the death of bacteria. A second mechanism is
gentamicin binds with 23s ribosomal rRNA and interacts with a protein to identify the stop