CASP Checklist: 12 Questions for Cohort Study Appraisal
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Added on 2023/06/03
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Learn how to appraise a cohort study with the CASP checklist. Answer 12 questions on validity, results, and local applicability. Use this educational tool to evaluate medical literature.
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2 SectionA:Aretheresultsofthestudyvalid? 1.Didthestudyaddressaclearly focusedissue? YesHINT:Aquestioncanbe intermsof •thepopulationstudied •theriskfactorsstudied •isitclearwhetherthest detectabeneficialorharmfuleff •theoutcomesconsidered Can’tTell No Comments: 2.Wasthecohortrecruitedin anacceptableway? YesHINT:Lookforselectionbiaswhich compromisethegeneralisabilityofthe findings: •wasthecohortrepresentativeofa definedpopulation •wastheresomethingspecialaboutthe cohort •waseverybodyincludedwhosho havebeen Can’tTell No Comments: Isitworthcontinuing? Yes Thestudywasconductedon3790menand1012womenfora 20yearperiod.Thepopulationdidnothavedepressivemoods whencompletingthehealthsurvey.Infollowuptheywere reported tospendtimeinTVwatchingandcarridingpriorto respondingona10-itemCenterforEpidemiologicStudies DepressionScale(CES-D10) Yes The participantsin the ACLS conducteda prospective study on population who had been examined at the Cooper Clinic in Dallas. All participants signed the consent form for the study.
3 3.Wastheexposureaccurately measuredtominimisebias? YesHINT:Lookformeasurementor classificationbias: •didtheyusesubjectiveor measurements •dothemeasurementstrulyreflect youwantthemto(havetheyb validated) •wereallthesubjectsclassified intoexposuregroupsusingthe sameprocedure Can’tTell No Comments: 4.Wastheoutcomeaccurately measuredtominimisebias? YesHINT:Lookformeasurementor classificationbias: •didtheyusesubjectiveor measurements •dothemeasurementstrulyreflect youwantthemto(havetheyb validated) •hasareliablesystembeen establishedfordetectingallthe measuringdiseaseoccurrence) •werethemeasurement methodssimilarinthedifferent •werethesubjectsand/or theoutcomeassessorblinded exposure(doesthismatter) Can’tTell No Comments: YES The study exposed all participants to sedentary behavior for similar period of time. The cohort study include a large proportion of population which helps establish its findings. Yes