Table of Included Studies on Cognitive Behavioral Therapy and Pharmacotherapy for Depression

Table of Included studies
Author
and Year
Title/ Keywords Objectives Methods Sample Key Findings Limitations
Wiles et.al,
2016
Long-term effectiveness
and cost-effectiveness
of cognitive behavioural
therapy as an adjunct to
pharmacotherapy for
treatment-resistant
depression in primary
care.
To find if CBT is useful
clinically for depression
that resisted treatment.
To find out if CBT can
help reduce costs for
depression that is
treatment refractory.
Carried out in
three UK
centres and
chose 73
general
practices to do
a random
controlled
clinical trial in
each.
The study chose
people between
the age of 18 to
75 who had taken
antidepressants
for a minimum of
six weeks but
still showed signs
of depression.
There was long-
term cost-
effectiveness of
combining CBT
with
pharmacotherapy
to treat
treatment-
resistant
depression.
There was lack
of resources to
enable face to
face answering
of questionaries.
Most of the
participants were
male making the
study
unbalanced.
Halverson,
2018
Cognitive Behavioral
Therapy for
Depression Medication.
To find out the efficiency
of using CBT for treating
depression
Searching for
data on clinical
trials where
CBT was used
to treat
depression.
Evaluation of the
data gathered on
the use of CBT to
treat depression
Using both
medication and
CBT to treat
depression has
advantages as
they work well
There are few
trials which
study the long-
term benefits of
CBT to treat
depression.

together.
Huhn,
2014
The Efficacy of
pharmacotherapy and
psychotherapy in
treating psychiatric
disorders in adults.
To analyse how effective
pharmacotherapy and
psychotherapy is in the
treatment of psychiatric
disorders.
To make a comparison of
the quality of clinical trials
for psychotherapy and
pharmacotherapy.
Searching the
databases of
Cochrane
Library,
PsycINFO, and
Medline to
gather data on
clinical trials.
The evaluation of
852 individual
clinical trials
carried out in 21
psychiatric
disorders.
A lot of research
exists on the
effectiveness of
the treatments on
their own, but
there is nothing
on a
combination of
the procedures.
There were few
data on
medications
because the
majority were
outdated.
Tolin, 2017 Can Cognitive
Behavioural Therapy
for Anxiety and
Depression Be
Improved with
Pharmacotherapy? A
Meta-analysis.
To find out if CBT can be
improved using
pharmacotherapy.
Searching data
on trials done
with a
combination of
CBT and
pharmacothera
py
Analysed data
from the chosen
controlled
clinical trials
where
pharmacology
was used in
addition to CBT
to treat patients
with anxiety and
depression
There are no
consistent
findings to show
that
pharmacotherapy
improves CBT.
Further studies
need to be done.
Little data is
available on the
subject to get
proper answers.