Cerebrovascular Accident: Pathophysiology and Pharmacologic Management

CEREBROVASCULAR ACCIDENT
CEREBROVASCULAR ACCIDENT
Name of the Student
Name of the university
Author’s note

1CEREBROVASCULAR ACCIDENT
Table of Contents
Introduction......................................................................................................................................2
Pathophysiology..............................................................................................................................2
Pharmacologic management............................................................................................................5
Conclusion.......................................................................................................................................6
References........................................................................................................................................8

2CEREBROVASCULAR ACCIDENT
Introduction
Stroke is a neurological disease that is the cause of death and disability all around the
world. The pathophysiology of the stroke is complicated and generally involves inflammatory
pathways, excitotoxicity, oxidative damage apoptosis, angiogenesis and ionic imbalances
(Brown et al.,2015). A stroke occurs when there is a sudden death of the cells in some of the
parts of the brain causing a lessening of the blood flow in the brain. This paper would describe
the pathophysiology of stroke linking with the symptoms manifested by Mr. Kwon. The paper
would also throw light on the pharmacological management in relation to the symptoms
displayed.
Pathophysiology
Ischeamic stroke can occur due to the sudden blockage of the cerebral artery. The region of the
brain supplied by this artery can become ischemic and can cause an infarct. And due to high
metabolic demands of brain an irreversible damage might occur within few minutes of ischemia
(Bullock & Hales, 2016).
The concerned patient might have suffered from Ischemia, which might have been
manifested in the form of thrombotic stroke, embolic stroke or systemic hypo perfusion or
venous thrombosis. Thrombosis might have occurred due to the deposition of the atherosclerotic
plaque within the walls of the arteries and a thrombi can easily develop on the surface of the
atherosclerotic lesions (Bullock & Hales, 2016). Low respiratory reserve and the complete
dependence of the aerobic metabolism make the tissues of the brain vulnerable to the effects of
ischemia. Thus a part of the brain parenchyma suffers from immediate death, while the others