1NURSING Question 1 AccordingtotheRoper,LoganandTierneymodelofnursingclinical diagnosis,judgment, assessment, intervention, and health evaluation must always be taken into consideration while dealing with the patient.This model of nursing places an emphasis on the capability of patients to effectively conduct activities of living (AL), and also elucidates the importance of promoting their independence. The most significant activities of living that are included in this model consists of communication, breathing, elimination, working, drinking, eating, playing, sleeping, control of body temperature, movement, dying, and death (Holland & Jenkins, 2019). On thoroughly evaluating the case study, it suggested that double resection surgery, which had been performed on the patient Ted due to malignant colorectal cancer, will significantly influence activities of living. Elimination, dressing, drinking and breathing will be severely affected by the surgery. In addition, not only will it result in impairment in mobility, but also lead to the onset of sleep disturbances. Post-operative patients have often been found to seek support and assistance from spiritual resources that help them cope with stressors of life, besides promoting their recovery (Groot et al., 2017).While there is lack of information on the cultural practices of the patient, if care is delivered in a manner that is not in alignment with his cultural ideas and philosophy, his recovery might be delayed. The surgery will significantly affect his emotional wellbeing, as well as result in considerable psychological stress and financial problems (Vargas et al., 2018). This in turn will act as an impediment to his recovery process. Poor psychological health will also be reported by his children, who do not live close to him. Question 2
2NURSING Colorectal cancer has been identified as the third most prevalent diagnosed cancer, all across the world.Additionally, it is the second leading malignancies for both genders, and incidence of novel cases of colorectal cancer, in addition to mortality have been gradually increasingoverthepastdecades,predominantlyamongstmiddle-agedandolder adults.Approximately 5% of all cases of colorectal cancer can be associated with two inherited syndromesthatare Lynchsyndromeand FamilialAdenomatousPolyposis(Recio-Boiles, Waheed & Cagir, 2019). A modification of the normal epithelium of a colon to precancerous lesions is soon followed by invasive carcinoma.This typically occurs due to genetic mutations thatareeithergermline(inherited)orsomatic(acquired).Inaddition,mismatchrepair, chromosomal instability, and CpG hypermethylation have been identified to be significantly associated with developments and progress of colorectal cancer.The theory that focuses on colonic carcinogenesis encompasses evolution of a clonal mutation that provides an advantage of cell survival immortality. This in turn stimulates development of a mutation in Wnt pathway, thereby leading to the generation of cancer hallmark like proliferation, metastasis or invasion (Basu, Haase & Ben-Ze'ev, 2016).According to research evidences colorectal cancer frequently originates from adenomatous polyps that are subjected to dysplastic changes, prior to the development of invasive carcinoma. The pathway of chromosomal consists of mutations that unbalance the tumour suppressor and oncogene equilibrium, as evidenced by adenomatous polyposis coli (APC), mutations (Kariv et al., 2020). Five major problems have been identified from the case study that are namely, obesity, risk ofcardiovascular complications, crackles during inspiration, persistent pain, and high body temperature. There is a growing body of evidence that suggests the presence of an association between being obese or overweight and increase in likelihood of acquiring mutations that cause
3NURSING colorectal cancer (Jochem & Leitzmann, 2016). Males reporting high BMI have a greater susceptibilityofbeingdiagnosedwithcolorectalcancer,incomparisontotheirfemale counterparts. Risk of suffering from a range of cardiovascular problems has also been associated with colorectal cancer. These patients are more likely to be affected with hypertension, heart failure, angina, and arrhythmia, which if left untreated, can also lead to death (Mazzari et al., 2018). Taking into consideration the fact that the patient has a history of heart failure,he needs to be administered medications for preventing any further cardiovascular complication. Inspiratory crackles provide an indication of excess fluid accumulation in the lungs, which in turn can be correlated with his heart failure history or presence of pneumonia. Reports of moderate postoperative pain that worsens at the time of palpation hint at presence of obstruction in the bowel, which might have resulted in vomiting and nausea (Chang et al., 2019). Postoperative pain has countless components such as, hyperalgesia that occurs in the region of theincision,centralneuronalsensitisation,localischemiaatthesiteofsurgery,and inflammatory response to the bowel resection surgery. Additionally, presence of postoperative fever characterized by temperature greater than 38°C can also be accredited to respiratory problem, or due to action of drugs. Moreover, the fever might have been caused due to venous thromboembolism, a potential surgical complication, or infection near the surgical site (Corkum et al., 2018). Question 3 Below given are the SMART goals and corresponding intervention for the five problems that have been identified in theprevious question:
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4NURSING Ted will be able to maintain our body temperaturenear 37° C, as evidenced by his vital signs, within 24 hours. The initial steps should focus on determining the underlying cause behind an increase in body temperature after the surgery.This should be followed by adjusting and monitoring environmental factors such as bed linen and room temperature, in order to accustomthem to the normal body temperature. Tedshall also be administered antipyretic medications for decreasing his body temperature (Mitchell, 2020). On using a numeric pain rating scale, Ted will demonstrate pain severity not more than 3, even during palpation, after 48 hours. In order to effectively conduct postoperative pain management, necessary steps should be followed for measuring his vital signs such as, blood pressure and heart rate, which often increase with an increase in pain severity. The response of the patient in relation to pain will also be adequately understood and acknowledged, since a delay in providing pain relief aggravates the condition, and also leads to worry and/or nervousness.The pharmacological intervention will focus on administration of nonsteroidal anti-inflammatory drug, ibuprofen that will provide an immediate relief from pain (Dwarica et al., 2020). Ted will no longer report inspiratory crackles, and a clear and open airway will be demonstrated through normal rate of respiration and normal breathing sounds, within 30 hours. The patient will first be assessed for airway patency, owing to the fact that inspiratory crackles and abnormal sounds of breathing suggest accumulation of excess fluid and secretion in the lungs. Adventitious breathing sounds shall also be checked, in order to identify any
5NURSING obstructionorresistanceintheairway.Thepharmacologicalinterventionwillfocuson administration of salbutamol, a bronchodilator that will trigger airway relaxation (Drug Bank, 2020). Ted will show compliance to a healthy diet that will eventually help in decreasing his body weight by as much as 1 lb within 1 week. The patient will be provided an explanation of the harmful impacts that obesity and being overweight can create on physical health, in relation to the co-morbid conditions that he might be susceptible to.This will be followed by motivating and encouraging the patient to show compliance to a healthy diet that contains high amount of dietary fibre, vegetables, whole grains, nuts, legumes and seeds (Mancini et al., 2016). He will also be administered diethylpropion, an appetite suppressant drug, which together with the dietary modification; will help in managing his body weight. Ted will report a pulse around 100 beats per minute and blood pressure around 120/80 mmHg, within 48 hours. Pharmaceutical management will focus on administration of the drug atenolol that will not only restore his blood pressure, but also reduce chance of angina and death due to heart attack (Drug Bank, 2020). The goal can also be accomplished by showing adherence to the dietary modification stated above. Question 4 Salbutamol belongs to the category of short-acting, selective β2agonists and will be administered for reducing inspiratory crackle. This drugwould prove effective by stimulating
6NURSING activation of the beta 2-adrenergic receptors that are located on the smooth muscles. This in turn would result in activation of adenyl cyclase and subsequently increase the amount of cyclic AMP. Protein kinase A would also get activated and directly inhibit phosphorylation of myosin.A decrease in the calcium concentration would help in relaxation of smooth muscle present in the airways, thus managing bronchoconstriction (Drug Bank, 2020). However, some adverseeffectsassociatedwiththisdrugarearrhythmia,tachycardia,drymouth, anxiety,angioedema, hypertension, irregular sleep pattern and headache. Atenolol belongs to the category of beta blockers, and has been found effective in management of hypertension and chest pain.The drug has been identified as a competitive beta- 1-adrenergicreceptorantagonist.Itwoulddirectlycompetewithsympathomimetic neurotransmitter and bind to the receptors. This would inhibit cardiac sympathetic stimulation by blocking the action of neurotransmitter on cardiac myocyte. Activation of adenyl cyclase would prevent cyclic AMP synthesis, eventually reducing activation of PKA, and preventing entry of calcium through voltage-gated calcium channels (Drug Bank, 2020). Some side effects are dizziness, nausea, tiredness, cold extremities, and depression. Postoperative management of a patient requires all nursing professionals to ensure that the patients are able to recover at a rapid rate, without being subjected to any health complication.In addition, postoperative management also comprises of appropriate pain relief, which if not addressed properly might worsen patient health outcomes and aggravate the situation. Hence, implementing the interventions discussed in the previous section would help nursing professionals to address the physical needs of the patient Ted, following bowel resection surgery.
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7NURSING References Basu, S., Haase, G., & Ben-Ze'ev, A. (2016). Wnt signaling in cancer stem cells and colon cancermetastasis.F1000Research,5. https://dx.doi.org/10.12688%2Ff1000research.7579.1 Chang, W. K., Tai, Y. H., Lin, S. P., Wu, H. L., Tsou, M. Y., & Chang, K. Y. (2019). An investigation of the relationships between postoperative pain trajectories and outcomes after surgery for colorectal cancer.Journal of the Chinese Medical Association,82(11), 865-871. https://journals.lww.com/jcma/Fulltext/2019/11000/An_investigation_of_the_relationshi ps_between.15.aspx Corkum, K. S., Hunter, C. J., Grabowski, J. E., & Lautz, T. B. (2018). Early postoperative fever workup in children: utilization and utility.Journal of pediatric surgery,53(7), 1295- 1300.https://doi.org/10.1016/j.jpedsurg.2017.06.019 Drug Bank. (2020).Atenolol. Retrieved fromhttps://www.drugbank.ca/drugs/DB00335 Drug Bank. (2020).Salbutamol. Retrieved fromhttps://www.drugbank.ca/drugs/DB01001 Dwarica, D. S., Pickett, S. D., Zhao, Y. D., Nihira, M. A., & Quiroz, L. H. (2020). Comparing ketorolac with ibuprofen for postoperative pain: a randomized clinical trial.Female PelvicMedicine&ReconstructiveSurgery,26(4),233-238. https://journals.lww.com/jpelvicsurgery/Abstract/2020/04000/Comparing_Ketorolac_Wit h_Ibuprofen_for.2.aspx
8NURSING Groot, M., Ebenau, A. F., Koning, H., Visser, A., Leget, C., Van Laarhoven, H. W., ... & Garssen, B. (2017). Spiritual care by nurses in curative cancer care: Protocol for a national, multicentre, mixed method study.Journal of advanced nursing,73(9), 2201- 2207.https://doi.org/10.1111/jan.13332 Holland, K., & Jenkins, J. (Eds.). (2019).Applying the Roper-Logan-Tierney Model in Practice- E-Book.ElsevierHealthSciences.https://books.google.co.in/books? hl=en&lr=&id=erKMDwAAQBAJ&oi=fnd&pg=PP1&dq=Cancer,+Colon+Holland,+K., +%26+Jenkins,+J.+(Eds.).+(2019).+Applying+the+Roper-Logan- Tierney+Model+in+Practice-E-Book.+Elsevier+Health+Sciences.Recio-Boiles %3B+Abdul+Waheed %3B+Burt+Cagir&ots=cB96u9RYIr&sig=vLLGJI7xgcd4vlz6cCgp0ZFNr8Q&redir_esc =y#v=onepage&q&f=false Jochem, C., & Leitzmann, M. (2016). Obesity and colorectal cancer. InObesity and Cancer(pp. 17-41). Springer, Cham.https://doi.org/10.1007/978-3-319-42542-9_2 Kariv, R., Caspi, M., Fliss‐Isakov, N., Shorer, Y., Shor, Y., Rosner, G., ... & Rosin‐Arbesfeld, R. (2020). Resorting the function of the colorectal cancer gatekeeper adenomatous polyposis coli.InternationalJournalofCancer,146(4),1064-1074. https://doi.org/10.1002/ijc.32557 Mancini, J. G., Filion, K. B., Atallah, R., & Eisenberg, M. J. (2016). Systematic review of the Mediterranean diet for long-term weight loss.The American journal of medicine,129(4), 407-415.https://doi.org/10.1016/j.amjmed.2015.11.028
9NURSING Mazzari, A., Tomaiuolo, P., Perrone, F., Sicoli, F., & Crucitti, A. (2018). Surgical management ofcolorectalcancerintheelderlypatient.InSurgicalmanagementofelderly patients(pp. 229-239). Springer, Cham.https://doi.org/10.1007/978-3-319-60861-7_14 Mitchell,K.J.(2020).PostoperativeFever.InThePerioperativeMedicineConsult Handbook(pp.405-411).Springer,Cham.https://doi.org/10.1007/978-3-030-19704- 9_52 Recio-Boiles, A., Waheed, A., & Cagir, B. (2019). Cancer, colon. InStatPearls [Internet]. StatPearls Publishing.https://www.ncbi.nlm.nih.gov/books/NBK470380/ Vargas, E. A., Mahalingam, R., Michaels, B., Cabrera, L., Campbell, E., & Liu, R. (2018). Perceptions of control in women undergoing cancer-related surgery on psychological perceptionsofhealth.SexRoles,79(3-4),218-227. https://www.researchgate.net/profile/Ramaswami_Mahalingam/publication/ 337706648_Vargas_Mahalingam_Liu_2017/links/5de62a8292851c83645d55b4/Vargas- Mahalingam-Liu-2017.pdf