This assignment provides a comprehensive overview of the relationship between obesity, diabetes, and sleep disorders. It includes a systematic review of studies on lifestyle interventions for obstructive sleep apnea (OSA), nicotine replacement therapy for smoking cessation, and the effects of lifestyle intervention in patients with type 2 diabetes. The assignment also discusses the pathogenic mechanisms and therapeutic approaches for obesity and OSA, as well as management strategies for hypertension in patients with diabetes mellitus.