Complications of Pregnancy: A Review on Hypertension Disorder and its Predictors

Running head: COMPLICATIONS OF PREGNANCY
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CHAPTER:22- COMPLICATIONS OF PREGNANCY

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Introduction
During pregnancy a women’s body goes through a lot of changes due to high level of
estrogen and progesterone. Mild nausea, abdominal pain, augmented blood volume etc are
some common discomforts felt by a pregnant woman. But in some cases, the symptoms may
be amplified and cause maternal disorders leading to complications in the pregnancy.
Complications of pregnancy are health related problems occurred during and after the
childbirth. There are two phases in the complication, the first phase which is termed as the
Obstetric labour Complication that occurs during the pregnancy. While the second phase are
the problems which arises after the pregnancy is called Puerperal Disorders (J.M.Alexander,
2013). According to Global Burden of Disease Study (GBD), 2017 there has been around 2.5
lakh deaths due to pregnancy globally. some major disorders are Hypertension, Gestational
diabetes mellitus, blood clotting disorder, placental disorder and many more which may
jeopardise foetus’s life and expose it to various diseases
To understand the complication of the pregnancy in a more efficient manner a report has been
chosen that focuses on the Pregnancy Induced Hypertension and its effect on the mother. It is
one of the major causes of maternal and foetal death and ill-health conditions.

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Discussion
U. Vivian Ukah, Dane A. De Silva, Beth Payne, Laura A. Magee et.al (2018). Prediction of
adverse maternal outcomes from pre-eclampsia and other hypertensive disorders of
pregnancy: A systematic review. Pregnancy Hypertension, 11, 115-123
Purpose of the article
The Hypertension Disorder of pregnancy (HDP) results in various maternal complications
such as eclampsia, stroke and impairment to the hepatic and renal organs. If these symptoms
are addressed using simple procedures it could aid in managing and overcoming these
complications. Thus, this research report focuses on accessibility of probable univariable
predictors (L.A. Magee, 2015). It also aims to review reports and predict the symptoms of the
Hypertension Disorder and state the worst maternal outcomes.
Literature Review
A literature review was conducted on Thangaratinam et.al report that focused on “Estimation
of proteinuria as a predictor of problems of pre-eclampsia”. This report stated that Proteinuria
was a faulty analyst of maternal complications. In his review uric acid level also was of
clinical usefulness and HELLP (haemolysis, elevated liver enzymes, low platelet count)
syndrome was an opposing outcome and was a common consequence. His review also reports
that the liver enzyme tests like AST, ALT and LDH were ordinary predictors of maternal and
foetal complications with preeclampsia. These tests did not possess any solid clinical utility
but their AUROCs shows a great level of distinction and can be investigated further for better
analysis.
Research Gap
There are many research’s done by numerous authors to identify various probable predictors
of maternal complications of pregnancies. This particular report is the first to identify the