Critical Appraisal Literature Review

Running head: CRITICAL APPRAISAL LITERATURE REVIEW
Critical Appraisal Literature Review
Name of the Student
Name of the University
Author Note:

1CRITICAL APPRAISAL LITERATURE REVIEW
1. What is the review purpose, objective or question?
The notable determination of the paper is to understand the efficacy of using Glascow
Coma Scale in juxtaposition with the extended pharmacologic thrombo-prophylaxis in order to
thwart Venomous Thrombo Embolism (VTE) after any kinds of abdominal and orthopedic
surgery.
VTE after the surgery is the reason behind numerous deaths in the recent times, the
researcher of the paper highlighted that most of the patients suffering from deep venous
thrombosis have the negative impact as it develops post-thrombotic syndrome (Milinis et al.,
2018). The risk of VTE exists even after weeks after discharging which is major concern in our
society. Thus the primary objective of the paper is to understand the importance of GCS in order
to prevent VTE in surgical patients.
2. Was there a published protocol for this review?
The paper have a published protocol as it was published in PROSPERO in the year 2017.
(Hussein 2017). The data of searching was 4th April 2017 considering the MEDLINE,
clinicaltrials.gov. and Embase and randomised controlled trails wren included in this paper. The
data of publication of the version is 12th April 2017. The entire procedure was managed by
National Institute for Health Research (NHS).
3. What are the inclusion criteria for this review?
The inclusion criteria for this review are discussed in the following table.
Criteria Inclusion Criteria
01 Participant must be a minimum of 21 days of
pharmacologic thromboprophylaxis
02 The Pharmacologic thromboprophylaxis

2CRITICAL APPRAISAL LITERATURE REVIEW
prevention technique must include low
molecular weight heparin, unfractionated
heparin, fondaparinux, Vitamin K, as well as
direct oral anti-coagulants.
03 Participants must be receiving prophylactic-
dose pharmacologic thromboprophylaxis
unaccompanied or in unification with
Glascow Coma Scale.
04 The recommendations from the manufacturers
must be considered regarding the closing and
the initialization of the Pharmacologic
thromboprophylaxis.
05 Participants must be a continuously using the
Glascow Coma Scale
06 Participants must be above 18 years of age.
07 Patients has to be going through Orthopedic
or abdominal surgery.
08 Venomous Thrombo Embolism (VTE) must
be confirmed with the help of imaging.
Table 1: Inclusion Criteria of the Criteria
(Source: Created by the author)
4. What types of studies were included?
This article included different types of studies from different time, studies were selected
based on the effectiveness of the research methodologies like total sample size and arm sample
size. Most studies based on hip replacement were considered in this paper along with that it can
be said long and short pharmacologic must be minimum of 20mg and 2.5mg. However,
mechanical duration of the after discharging were not considered in the paper. 1231 studies were
considered in this paper for this systematic review. The paper also considered the pharmacologic
agents such as Parental, Enoxaparin 40mg OD.
5. What databases/search engines were searched?