Cushing Syndrome: Causes and Symptoms

Running head: CUSHING SYNDROME
CUSHING SYNDROME
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1
CUSHING SYNDROME
Answer 1:
Cushing syndrome mainly occurs due to tumors and due to medication. Tumor is mainly
the endogenous cause of Cushing syndrome and is the less common cause of the disorder. The
tumors may be both cancerous as well as non-cancerous. Medication is mainly seen to be the
most common exogenous cause of the occurrence of Cushing syndrome as it originates outside
the body. Researchers are of the opinion that cortisol-like steroid drugs as well as glucose-
corticoids are some of the medications that had been intricately linked with the occurrence of the
Cushing syndrome (Isidori, 2015). Medications of certain disorders that act as the risk factor of
the Cushing syndrome are allergies, asthma as well as autoimmune system that attack its own
tissues or organ transplantation. In case of the patient, it is seen that she takes a medication called
betamethosone that is used for the treatment of asthma for many years (Dalmazi & Reincke,
2018). Therefore, this medication might have been the main cause of the occurrence of Cushing
syndrome. In the normal cases, hypothalamus helps in production of corticotrophin that
stimulates the pituitary gland to release the ACTH hormone or the adrenocorticotrophic hormone
(Lonser, Nieman, & Oldfield, 2017). Then ACTH stimulates the adrenal glands to produce
cortisol. When the levels of cortisol increase in blood due to occurrence of tumor or due the use
of medications mainly steroids, it results in development of the disorder. In case of the patient,
her medication taken for asthma is the main cause of occurrence of Cushing syndrome.
Answer 2:
Some of the most common sign and symptoms involve progressive obesity as well as
skin changes. Researchers are of the opinion that weight gain and fatty tissue mainly around the
midsection and upper back and in the face and between the shoulders. Pink and purple stretch