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The article discusses the characteristics of people included in the sample at the baseline examination, characterization of people with casual serum glucose >200 mg/dL, multivariable analysis of variables associated with casual serum glucose level, and changes in casual serum glucose level between baseline and follow-up examination.
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1.Describe the characteristics of the people included in the sample at the baseline examination. At the baseline examination, data from 3950 people were collected in terms of sex, education level, age, Serum total cholesterol, Systolic blood pressure, Diastolic blood pressure, Current cigarette smoking, Number of cigarettes smoked each day, Body mass index, use of anti- hypertensive medication, Casual serum glucose. Out of 3950, 1725 are male and 2225 are female. 41.1 % people are education level 0-11 years where as 28.6% are diploma holder.49.1 % people are currently smoker at baseline examination whereas 50.1% are not currently smoker. Only 3.1% people use anti hyper tension mediation. At baseline examination, mean serum total cholesterol is 237.41mmg/dL with standard deviation 44.779.Mean age of people at baseline examination is 49.95 years with standard deviation 8.644 years. Mean systolic blood pressure is 132.838 mmHg with standard deviation 22.3993. Mean systolic blood pressure is 83.047 mm/Hg with standard deviation 12.0522. People averagely smoke 8.87 cigarettes every day with standard deviation 11.844. At baseline examination people have average BMI 25.8523 Kg/m2 with standard deviation 4.07827. Mean casual serum glucose is observed as 82.18 mmg/dL with standard deviation 24.485. 2.Characterize the people who had casual serum glucose >200 mg/dL at the baseline examination and compare them to people who had ≤200 mg/dL casual serum glucose at the baseline examination in terms of age, body mass index (BMI), education and whether they were taking blood pressure medication at the time of the baseline examination. We group the variable in two categories: 1: casual serum glucose >200 mg/dL at the baseline examination 2 : casual serum glucose≤200 mg/dL at the baseline examination
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Following table shows the descriptive statistics for the group 1 and 2 for age and BMI Descriptive Statistic Age at baseline exam (years) Body Mass Index at baseline exam (kg/m^2) Group 1Group 2Group 1Group 2 Mean55.7149.9428.356525.8425 Size313556313556 Median564928.525.425 Variance45.2874.61331.24516.388 Std. Deviation6.7298.6385.589694.04821 Minimum433217.1715.54 Maximum677043.6756.8 Range243826.541.26 Interquartile Range10147.394.99 Skewness-0.2490.1990.4070.961 Kurtosis-0.79-1.0140.762.507 We have 31 people having casual serum glucose >200 mg/dL at the baseline examination and 3556 people having casual serum glucose≤200 mg/dL at the baseline examination. Mean age of people having casual serum glucose >200 mg/dL at the baseline examination is 55.71 (6.729) years whereas mean age of people having casual serum glucose≤200 mg/dL at the baseline examination is 49.94(8.638) years. BMI of group 1 is higher than group 2. One can observed the difference between other statistic from above table. 64.51 % people having casual serum glucose >200 mg/dL at the baseline examination has education 0-11 years whereas for other group this percentage is 42.28%. In Group 1 19.35% people are diploma holder whereas in Group 2 29.33% people are diploma holders. There is no one in Group 1 which has college degree or more whereas in Group 2 about 12% people have college degree or more. 9% People in group 1 taking mediation whereas only 3% people in Group 2 are taking medication for controlling the blood pressure.
3.Are the results from the bivariate comparisons above (point 2) different if the actual casual serum glucose level at baseline examination is analysed, rather than the dichotomized glucose variable? No, the results from the bivariate comparisons above (point 2) different if the actual casual serum glucose level at baseline examination is analysed, rather than the dichotomized glucose variable. 4.Considering only individuals with casual serum glucose level at baseline below 200 mg/dL, which of these variables (age, BMI, education and whether they were taking blood pressure medication) are significantly associated with casual serum glucose level at baseline in a multivariableanalysis?Describetheirrelationshipwithcasualserumglucoselevel, including which variables explain the most variation in casual serum glucose level. Report the ‘minimum model’ obtained. Explain any differences you observe between the results of the bivariate analysis in point 3 above and multivariable analysis. We considered the individuals with casual serum glucose level at baseline below 200 mg/dL. There are 3568 people having casual serum glucose level at baseline below 200 mg/dL. To test whether there is any significant relation between the casual serum glucose level at baseline and independent variables (age, BMI, education and whether they were taking blood pressure medication). We run the multiple regression analysis. In the independent variables Education and whether they were taking blood pressure medication are categorical variables, we need to create dummy variables for testing the above hypothesis, we create four dummy variables (3 for education and 1 for whether they were taking blood pressure medication. We take 1-11 years education and not taken any medication as a reference variable. Following table shows the ANOVA of multiple regression analysis: Source of Variation Sum of SquaresdfMean SquareFP- Value Regression16607.0562767.84212.840
Residual765023.73549215.56 Total781630.73555 The P-value = 0 suggest that there issignificant relation between the casual serum glucose level at baseline and independent variables (age, BMI, education and whether they were taking blood pressure medication). That is at least one of the coefficient is non zero. From following table we can see that which coefficient are significant or not. Independent VariableCoefficientStd. ErrortP Value (Constant)63.4852.19728.8990.000 Age at baseline exam (years)0.1920.0306.4710.000 Body Mass Index at baseline exam (kg/m^2)0.2890.0624.6400.000 HighSchoolDiploma-0.0970.612-0.1590.873 Some College and Vocation-0.3990.729-0.5470.584 degree and more-0.0870.822-0.1060.916 taken or not-0.7721.423-0.5420.588 We can see that only age and BMI are significant whereas other variables education and whether they were taking blood pressure medication are found to be non-significant for predicting the casual serum glucose level at baseline. Both age and BMI have positive correlation with casual serum glucose level at baseline. As the education and whether they were taking blood pressure medication are found to be non- significant for predicting the casual serum glucose level at baseline, we fit the model again using age and BMI variables only. Following is the equation of multiple regression analysis for predicting the casual serum glucose level at baseline using age and BMI as a predictor variables. Casual serum glucose level at baseline = 63.35 + 0.192 × Age + 0.29 × BMI Each incline in age results in 0.192 incline in casual serum glucose level whereas each unit of BMI incline results in 0.29 incline in casual serum glucose level. From bivariate analysis, we observed that mean age and BMI for person having casual serum glucose >200 mg/dL at the baseline examination is more than the person having casual serum
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glucose≤200 mg/dL at the baseline examination. And from the multivariate analysis we observed that each icline in age and BMI results in incline in the casual serum glucose level. 5.Did the casual serum glucose level change significantly between the baseline examination and the follow-up examination? Is this result the same when casual serum glucose level is categorised according to the clinical threshold of >200 mg/dL versus ≤200 mg/dL? We carry the paired t test for the testing whether there is casual serum glucose level change significantly between the baseline examination and the follow-up examination. We observed t statistics is -1.854 and P- value is 0.064 < 0.1 suggest that there is significant change in the casual serum glucose level change significantly between the baseline examination and the follow-up examination at 10% level of significance. We now group the people having casual serum glucose >200 mg/dL and casual serum glucose≤ 200 mg/dL. After that we used paired t test for both the groups. We observed t statistics is 3.124 and P- value is 0.008 < 0.1 suggest that there is significant change in the casual serum glucose level >200 mg/dL change significantly between the baseline examination and the follow-up examination at 10%. We observed t statistics is -2.675 and P- value is 0.008 < 0.1 suggest that there is significant change in the casual serum glucose level≤200 mg/dL change significantly between the baseline examination and the follow-up examination at 10%. From the test statistics we can observed that glucose level increases for people having casual serum glucose level >200 mg/dL at baseline examination and glucose level decreases for people having casual serum glucose level <= 200 mg/dL at baseline examination.
SPSS Output: Sex FrequencyPercentValid Percent Cumulative Percent ValidMale172543.743.743.7 Female222556.356.3100.0 Total3950100.0100.0 Education level FrequencyPercentValid Percent Cumulative Percent Valid0-11 years162541.142.242.2 High school diploma113128.629.471.6 Some college, vocational school63816.216.688.2 College degree or more45611.511.8100.0 Total385097.5100.0 MissingSystem1002.5 Total3950100.0 Current cigarette smoking at baseline exam FrequencyPercentValid Percent Cumulative Percent ValidNot current smoker200950.950.950.9 Current smoker194149.149.1100.0 Total3950100.0100.0
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Use of anti-hypertensive medication at baseline exam FrequencyPercentValid Percent Cumulative Percent ValidNot currently used377195.596.896.8 Current use1243.13.2100.0 Total389598.6100.0 MissingSystem551.4 Total3950100.0 casual serum at baseline exam FrequencyPercentValid Percent Cumulative Percent Valid1356890.399.199.1 232.8.9100.0 Total360091.1100.0 MissingSystem3508.9 Total3950100.0
Descriptive Statistics NMeanStd. Deviation Age at baseline exam (years)395049.958.644 Systolic blood pressure at baseline exam (mmHg)3950132.83822.3993 Diastolic blood pressure at baseline exam (mmHg)395083.04712.0522 Number of cigarettes smoked each day at baseline exam 39208.8711.824 Body Mass Index at baseline exam (kg/m^2)393225.85234.07827 Serum total cholesterol at baseline exam (mmg/dL)3904237.4144.779 Casual serum glucose at baseline exam (mg/dL)360082.1824.485 Valid N (listwise)3552 Q2 Case Processing Summary NewVar Cases ValidMissingTotal NPercentNPercentNPercent Age at baseline exam (years)13196.9%13.1%32100.0% 2355699.7%12.3%3568100.0% Body Mass Index at baseline exam (kg/m^2) 13196.9%13.1%32100.0% 2355699.7%12.3%3568100.0%
Education level * NewVar Crosstabulation Count NewVar Total12 Education level0-11 years2014701490 High school diploma610201026 Some college, vocational school5572577 College degree or more0415415 Total3134773508 Use of anti-hypertensive medication at baseline exam * NewVar Crosstabulation Count NewVar Total12 Use of anti-hypertensive medication at baseline exam Not currently used2934023431 Current use3113116 Total3235153547 Q3:
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Skewness.199.041 Kurtosis-1.014.082 Body Mass Index at baseline exam (kg/m^2) 1Mean28.35651.00394 95% Confidence Interval for Mean Lower Bound26.3061 Upper Bound30.4068 5% Trimmed Mean28.1757 Median28.5000 Variance31.245 Std. Deviation5.58969 Minimum17.17 Maximum43.67 Range26.50 Interquartile Range7.39 Skewness.407.421 Kurtosis.760.821 2Mean25.8425.06789 95% Confidence Interval for Mean Lower Bound25.7094 Upper Bound25.9756 5% Trimmed Mean25.6369 Median25.4250 Variance16.388 Std. Deviation4.04821 Minimum15.54 Maximum56.80 Range41.26 Interquartile Range4.99 Skewness.961.041 Kurtosis2.507.082 Q4: DATASETCOPYQ4. DATASETACTIVATEQ4.
FILTEROFF. USEALL. SELECTIF(NewVar=2). DATASETACTIVATEDataSet1. EXECUTE. DATASETACTIVATEQ4. DATASETACTIVATEDataSet1. SAVEOUTFILE='C:\Users\RajuChavan\Downloads\assignmentstats.sav'/COMPRESSED. DATASETACTIVATEQ4. SAVEOUTFILE='C:\Users\RajuChavan\Desktop\RR.xlsx'/COMPRESSED. DATASETACTIVATEDataSet1. DATASETACTIVATEDataSet1. DATASETCLOSEQ4. DATASETCOPYQ4. DATASETACTIVATEQ4. FILTEROFF. USEALL. SELECTIF(NewVar=2). DATASETACTIVATEDataSet1. EXECUTE. DATASETACTIVATEQ4. RECODEeduc(2=1)(ELSE=0)INTOEdu1. VARIABLELABELSEdu1'HighSchoolDiploma'. EXECUTE. RECODEeduc(3=1)(ELSE=0)INTOVocation. VARIABLELABELSVocation'SomeCollegeandVocation'. EXECUTE. RECODESEX(4=1)(ELSE=0)INTODegree. VARIABLELABELSDegree'CollegeDegreeandmore'. EXECUTE. RECODEBPMEDS.1(1=1)(ELSE=0)INTOMeditation. VARIABLELABELSMeditation'takenornot'. EXECUTE. Variables Entered/Removedb Model Variables Entered Variables RemovedMethod 1taken or not, HighSchoolDiplo ma, Body Mass Index at baseline exam (kg/m^2), degree and more, Age at baseline exam (years), Some College and Vocationa .Enter a. All requested variables entered. b. Dependent Variable: Casual serum glucose at baseline exam (mg/dL)
Model Summary ModelRR Square Adjusted R Square Std. Error of the Estimate 1.146a.021.02014.682 a. Predictors: (Constant), taken or not, HighSchoolDiploma, Body Mass Index at baseline exam (kg/m^2), degree and more, Age at baseline exam (years), Some College and Vocation ANOVAb ModelSum of SquaresdfMean SquareFSig. 1Regression16607.05062767.84212.840.000a Residual765023.6643549215.560 Total781630.7143555 a. Predictors: (Constant), taken or not, HighSchoolDiploma, Body Mass Index at baseline exam (kg/m^2), degree and more, Age at baseline exam (years), Some College and Vocation b. Dependent Variable: Casual serum glucose at baseline exam (mg/dL) Coefficientsa Model Unstandardized Coefficients Standardized Coefficients tSig.BStd. ErrorBeta 1(Constant)63.4852.19728.899.000 Age at baseline exam (years).192.030.1126.471.000 Body Mass Index at baseline exam (kg/m^2).289.062.0794.640.000 HighSchoolDiploma-.097.612-.003-.159.873 Some College and Vocation-.399.729-.010-.547.584 degree and more-.087.822-.002-.106.916 taken or not-.7721.423-.009-.542.588 a. Dependent Variable: Casual serum glucose at baseline exam (mg/dL)
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ANOVAb ModelSum of SquaresdfMean SquareFSig. 1Regression16477.43528238.71738.257.000a Residual765153.2793553215.354 Total781630.7143555 a. Predictors: (Constant), Body Mass Index at baseline exam (kg/m^2), Age at baseline exam (years) b. Dependent Variable: Casual serum glucose at baseline exam (mg/dL) Coefficientsa Model Unstandardized Coefficients Standardized Coefficients tSig.BStd. ErrorBeta 1(Constant)63.3502.00931.526.000 Age at baseline exam (years).192.029.1126.679.000 Body Mass Index at baseline exam (kg/m^2).290.061.0794.727.000 a. Dependent Variable: Casual serum glucose at baseline exam (mg/dL) Q5 Paired Samples Statistics MeanNStd. DeviationStd. Error Mean Pair 1Casual serum glucose at baseline exam (mg/dL)81.04282420.073.378 Casual serum glucose at follow-up exam (mg/dL)81.83282422.270.419
Paired Samples Correlations NCorrelationSig. Pair 1Casual serum glucose at baseline exam (mg/dL) & Casual serum glucose at follow-up exam (mg/dL) 2824.438.000 Paired Samples Test Paired Differences MeanStd. DeviationStd. Error Mean 95% Confidence Interval of the Difference LowerUpper Pair 1Casual serum glucose at baseline exam (mg/dL) - Casual serum glucose at follow-up exam (mg/dL) -.78522.513.424-1.616.045 For Group 1: Paired Samples Statistics MeanNStd. DeviationStd. Error Mean Pair 1Casual serum glucose at baseline exam (mg/dL)271.361469.37318.541 Casual serum glucose at follow-up exam (mg/dL)211.001464.70917.294 Paired Samples Correlations NCorrelationSig. Pair 1Casual serum glucose at baseline exam (mg/dL) & Casual serum glucose at follow-up exam (mg/dL) 14.420.135
Paired Samples Test Paired Differences MeanStd. DeviationStd. Error Mean 95% Confidence Interval of the Difference LowerUpper Pair 1Casual serum glucose at baseline exam (mg/dL) - Casual serum glucose at follow-up exam (mg/dL) 60.35772.29819.32218.613102.101 For Group 2: Paired Samples Statistics MeanNStd. DeviationStd. Error Mean Pair 1Casual serum glucose at baseline exam (mg/dL)80.10281014.186.268 Casual serum glucose at follow-up exam (mg/dL)81.19281019.887.375 Paired Samples Correlations NCorrelationSig. Pair 1Casual serum glucose at baseline exam (mg/dL) & Casual serum glucose at follow-up exam (mg/dL) 2810.231.000
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Paired Samples Test Paired Differences MeanStd. DeviationStd. Error Mean 95% Confidence Interval of the Difference LowerUpper Pair 1Casual serum glucose at baseline exam (mg/dL) - Casual serum glucose at follow-up exam (mg/dL) -1.09021.598.407-1.889-.291 References: Abbott, M. L. (2016).Using Statistics in the Social and Health Sciences with SPSS and Excel. John Wiley & Sons. Bickel, P. J., & Doksum, K. A. (2015).Mathematical statistics: basic ideas and selected topics, volume I (Vol. 117). CRC Press. Chatterjee, S., & Hadi, A. S. (2015).Regression analysis by example. John Wiley & Sons. Darlington, R. B., & Hayes, A. F. (2016).Regression analysis and linear models: Concepts, applications, and implementation. Guilford Publications. Draper, N. R., & Smith, H. (2014).Applied regression analysis (Vol. 326). John Wiley & Sons. Fox, J. (2015).Applied regression analysis and generalized linear models. Sage Publications. Glantz, S. A., Slinker, B. K., & Neilands, T. B. (2016).Primer of applied regression & analysis of variance. McGraw-Hill Medical Publishing Division. Larson-Hall, J. (2015).A guide to doing statistics in second language research using SPSS and R. Routledge.
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