NRS 624: Advanced Pathopharmacology - Drug and IV Calculations

This assignment focuses on drug and IV calculations within the context of NRS 624: Advanced Pathopharmacology. It includes exercises covering dosage calculations based on doctor's orders and available supplies, prescription completion involving single and daily doses of medications like Ampicillin, Digoxin, and Lasix, and the calculation of IV flow rates using different drop factors and infusion times. The calculations demonstrate the application of formulas to determine correct medication amounts and IV administration rates, ensuring patient safety and accurate drug delivery. This document is helpful for students to practice and understand the principles of drug and IV calculations in a clinical setting. Desklib provides a platform to access this document and similar resources to support student learning.

NRS 624: Advanced Pathopharmacology
ASSIGNMENT
Worksheet 2
Drug and IV Calculation
Dosage Formula:
Doctor’s Order (D) x quantity (Q) = individual dosage to be administered
Supply on Hand (H)
Short version: D x Q = one dose
H
The formula can be read as: The doctor’s order (the numerator) divided by the supply on
hand (the denominator), multiplied by the quantity equals the amount of one dose of
medication.
Important: The doctor’s order and the supply on hand must be in the same unit of measure,
such as grams (g), milligrams (mg), and milliliters (ml). Answers must include the correct
unit notation.
Example: Dr. Khalid has prescribed 30 mg of medicine for his patient. The drug label on the
medicine indicates that the medicine is supplied in 60 mg per tablet. We will use the dosage
formula to calculate the correct amount of medication for one dose.
(D) 30 mg x (Q) 1 tablet = 0.5 mg Therefore, one dose will be one half
tablet.
(H) 60 mg
Important: In the medical field, any decimal number that is not greater than should have a 0 in front of the
decimal point. Thus, the correct form for the dosage in this example is 0.5 mg, not .5 mg.

NRS 624: Advanced Pathopharmacology
EXERCISE 1:
Calculate the dosage for the following. COMPUTATIONS
1. Order: 500 mg 2 tablet will be delivered as one dose.
Supply on hand: 250 mg per tablet
2. Order: 1 g 2 tablet will be delivered as one dose
Supply on hand: 0.5 g per capsule
3. Order: 50 mg 10 ml of medicine tablet will be
delivered as one dose.
Supply on hand: 25 mg per 5 ml
4. Order: 1000 mg Half of one tablet will be delivered as
one dose.
Supply on hand: 2000 mg per scored tablet
5. Order: 500 mg 4 capsule tablet will be delivered as one
dose.
Supply on hand: 125 mg per caplet
6. Order: 250 mg 2 capsule will be delivered as one dose
Supply on hand: 125 mg per capsule
7. Order: 25 mg 5 ml of medicine will be delivered as
one dose
Supply on hand: 100 mg per 20 ml
8. Order: 75 mg 300 ml of medicine will be delivered as
one dose
Supply on hand: 5 mg per 20 ml
9. Order: 5 mg 1.25 ml of medicine will be delivered
as one dose
Supply on hand: 32 mg per 8 ml
10
.
Order: 500 mg 20 ml of medicine will be delivered as
one dose
Supply on hand: 50 mg per 2 ml

NRS 624: Advanced Pathopharmacology
EXERCISE 2:
Prescription Single dose Daily dose Complete
prescription
Ampicillin 500 mg po qid x 5
d
On hand: 250 mg capsules
2 capsules will
be delivered as
one dose
8 capsules will be
delivered daily
40 capsules
Digoxin elixir 150 mcg po tid
x 10 d
On hand: 50 mcg/ml
3 ml of
medicine will
be delivered as
one dose
9 ml of medicine
will be delivered
daily
90 ml
Codeine sulfate 60 mg po q4h
x 7 d
On hand: 30 mg tablets
2 tablet will be
given as one
dose
12 tablet will be
given daily
84 tablets
Clonidine 0.4 mg po bid x 3 d
On hand: 0.1 mg tablets
4 tablets will be
delivered as
one dose
8 tablet will be
delivered daily
24 tablet
Amoxicillin 250 mg po qid x
10 d
On hand: 125 mg capsules
2 capsules will
be delivered as
one dose
8 capsules will be
delivered daily
80 capsules
Lasix 40 mg po qid x 30 d
On hand: 20 mg tablets
2 tablets will be
delivered as
one dose
8 tablets will be
delivered daily
240 tablets
Ampicillintrihydrate 250 mg
po qid x 10 d
On hand: 125 mg per 5 ml
10 ml will be
delivered as
one dose
40 ml will be
delivered daily
400 ml
Dilaudid 1.5 mg IM od x 3 d
On hand: 0.6 mg per ml
2.5 ml will be
delivered as
one dose
2.5 ml will be
delivered daily
7.5 ml
Gentamicin 4 mg/kg for a 74
kg patient
IV bid x 7d
On hand: 40 mg/ml, 2 ml
ampoules
7.4 ml will be
given as one
dose
14.8 ml will be
delivered in a day
103.6 ml

NRS 624: Advanced Pathopharmacology
CALCULATING IV FLOW RATES
In order to calculate the IV flow rate, you must know the total volume to be infused, the time
in minutes, and the drop factor. The drop factor is the rate at which medicine flows through
the IV line into the body. The three main drop factors for IV administration sets are:
Blood drip factor = 10 gtts/ ml
Standard drip factor = 15 gtts/ ml
Microdrip factor = 60 gtts/ ml
The formula for calculating IV flow rates is:
Total volume (ml) X drop factor (gtts/ ml) = gtts/ min (flow rate)
Time (in minutes)
Example: 1500 ml IV Saline is ordered over 12 hours. Using a drop factor of 15 gtts/ ml,
how many drops per minute (gtts/ min) need to be delivered?
1500 ml X 15 (gtts/ ml) = 31gtts/ min (flow rate)
12 x 60
EXERCISE 3:
Calculate the IV flow rate for each of the following
1. 500 ml to run over 6 hours. The drop factor is 20 gtts/ ml.
The flow rate will be 27.8 gtts/min
2. 1000 ml to be delivered over 12 hours. The drop factor is 15 gtts/ ml.
The flow rate will be 20.8 gtts/min
3. 650 ml to infuse over 4 hours. The drop factor is 10 gtts/ ml.
The flow rate will be 27.08 gtts/min

NRS 624: Advanced Pathopharmacology
4. 100 ml to be delivered over 40 minutes. The drop factor is 20 gtts/ ml.
The flow rate will be 50 gtts/min
5. 250 ml to infuse over 2 hours. The drop factor is 15 gtts/ ml.
The flow rate will be 31.25 gtts/min
6. 2000 ml to run over 24 hours. The drop factor is 60 gtts/ ml.
The flow rate will be 83.33 gtts/min
7. 1200 ml to run over 12 hours using a microdrip infusion set.
The flow rate will be 100 gtts/min
8. 50 ml to be infused in 30 minutes with a drop factor of 15 gtts/ ml.
The flow rate will be 25 gtts/min
9. 650 ml to infuse in 10 hours with a blood drip factor.
The flow rate will be 10.83 gtts/min
10. 750 ml to run over 5 hours using IV tubing with a drop factor of 20 gtts/ ml.
The flow rate will be 50 gtts/min