Table of Contents INTRODUCTION...........................................................................................................................1 MAIN BODY...................................................................................................................................1 CONCLUSION................................................................................................................................3 REFERENCES................................................................................................................................4
INTRODUCTION Alcohol abuse refers to pattern of drinking too much alcohol very often which is a serious problem for people. It consist the habit of an individual to intake excess amount of alcohol on regular basis and it may leads to physical dependency on alcohol (Holzhauer, Zenner and Wulfert, 2016). The present report will focus on effects of alcohol abuse on the body including endocrine system. MAIN BODY Excess use of alcohol is harmful for body and create several types of health problems for an individual. It is necessary for people to avoid use of alcohol for remain healthy because it is responsible fore creating number of problem in functioning of human body. Initially, some of short term effectsdue to intake of alcohol which consist skin flushing, loss of coordination, loss of critical judgement, dulled perception, mood swings and reduced core body temperature. It also consistraisedbloodpressure,passingout,vomiting,loweredinhibitionsandtrouble concentrating. In addition to this, it involveslong term effectssuch as memory loss, trouble learning, diminished grey matter & white matter in the brain, alcoholic hepatitis and liver fibrosis (Parker,Kim and Gao, 2018). It also includes steatosis (fatty liver), throat, mouth, larynx, breast, liver,colorectalor oesophagealcancer,highbloodpressure,cardiomyopathy,strokeand irregular heart beat. At the other hand, it has been analyse that excess intake of alcohol may responsible for developing a critical situation of alcohol poisoning. It consist symptoms ofalcohol poisoning such as confusion, nausea & vomiting, slowed or irregular breathing, cyanosis or a blue tinted skin, pale skin, low body temperature or hypothermia, unconscious and seizures. However, it is analysed that several physical and psychological effects are observed in people who prefer to intake excess amount of alcohol on daily basis (Pathophysiology of the Effects of Alcohol Abuse on the Endocrine System,2017). Moreover, it is evaluated that chronic heavy drinking is connected with different kinds of serious health issues. Physical effects Liver– The excess intake of amount of alcohol is responsible for creating liver disease because liver may become inflamed or scarred. It consist several situation including fatty liver, cirrhosis and fibrosis or a person may also develop liver cancer. 1
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Digestive system– The alcohol intake can wear down lining of stomach and boost up secretion of hydrochloric acid which may contribute to ulcers. It may also interfere in context of absorption, storage, nutrient breakdown, transportation and excretion which may leads to deficiencies nutrient or trouble in complete utilising them. Pancreas– The use of alcohol promote pancreatic secretion of harmful materials that can results into the problem of pancreatitis which impairs digestion (Benjamin and et. al., 2017). Central nervous system (CNS)– This involves the deficiency of Thiamine or vitamin B1 that is linked with chronic heavy drinking which can results into Wernicke – Korsakoff syndrome including symptoms like learning, problems, memory difficulties, confusion and impaired coordination. Cardiovascular (CV) health– The habit of consuming too much amount of alcohol is responsible for developing problems like stroke, irregular heartbeat, high blood pressure, blood clots, heart attack, trouble in pumping blood through the body and cardiomyopathy. Excessive alcohol, use results into anaemia through malnutrition (How Alcohol Can Impair the Body's Hormone System, 2019). Reproductive health– The consuming behaviour of excess alcohol create various kinds of reproductive problems in an individual which consist erectile dysfunction and irregular menstruation. However, both male and female may face reduced fertility for long term due to heavy drinking and use of alcohol by pregnant women may increase risk of miscarriage, stillbirths or having baby with fetal alcohol spectrum disorder (FASD). Psychological effects This consist the fact that excessive utilisation of alcohol may lards to different types of mental health problems such asalcohol induced psychiatric syndromesincluding depression, bipolardisorder,sleepingproblemsetc.however,itwillalsoresultsintoseveralother psychologicalissueincludinganxiety,schizophrenia,majordepressionandmanymore (Gonçalves and et. al., 2016). Effects of alcohol abuse on Endocrine system The endocrine system consist hypothalamic pituitary adrenal axis, the hypothalamic pituitary gonadal axis, the hypothalamic pituitary thyroid axis, the hypothalamic pituitary growth hormone/insulin like growth factor-1 axis and hypothalamic posterior pituitary axis. It also involves sources of hormones like endocrine adipose tissue and endocrine pancreas. In addition 2
to this,endocrine systemconsist secretion and storage of hormones which get disrupted by use of excessalcoholby n individual.Meanwhile,hormonesare responsiblefor production, utilisation & storage of energy and reproduction for creation of new life. Moreover, they provide support to conducting proper maintenance of body systems which plays an important role in order to regulate the blood pressure as well as body mass (Caputo,Wood and Jabbour, 2016). The major functions conducted by different types of organs systems get disrupted due to too much consuming habit of alcohol. It consist that alcoholimpairs the blood sugar levels which are maintained by insulin and raise by glycogen. However, this harmful substance is responsible for interfering the all sources of sugar as well asinterrupt hormoneswhich has functioning to balance the glucose levels as itlimits intake of glucose, inhibit glucose production,augmentsinsulinsecretionandimpairshormonalresponsetowards hypoglycaemia. Moreover, acute alcohol consumption can cause PTH deficiency, increase calcium production and disturb vitamin D metabolism (Ward,Oswald and Galante, 2016). It may limit an adequate absorption of dietary calcium, inhibit function of bone forming cells and alter reproductive hormones. At the other hand, it has been analysed that different types ofalcohol induced hormonal dysregulationare responsible for affecting entire body and develop various disorders. It involves reproductive deficits, body growth defect. Stress abnormalities, cancers, thyroid problems, immune dysfunction, bone disease and psychological & behavioural disorders. CONCLUSION From the above report, it has been concluded that alcohol abuse can be described as excess use of it which is harmful for body and create several types of health problems for an individual. It impacts on several body parts such as liver, digestive system, pancreas, central nervous system (CNS), cardiovascular (CV) health and reproductive health along with certain psychological effects. 3
REFERENCES Books and journals Holzhauer, C.G., Zenner, A. and Wulfert, E., 2016. Poor body image and alcohol use in women.Psychology of Addictive Behaviors,30(1), p.122. Parker, R., Kim, S.J. and Gao, B., 2018. Alcohol, adipose tissue and liver disease: mechanistic linksandclinicalconsiderations.NatureReviewsGastroenterology& Hepatology,15(1), p.50. Benjamin, E.R. and et. al., 2017. The effects of body mass index on complications and mortality after emergency abdominal operations: the obesity paradox.The American Journal of Surgery,214(5), pp.899-903. Gonçalves, J. and et. al., 2016. Effects of drugs of abuse on the central neuropeptide Y system.Addiction biology,21(4), pp.755-765. Caputo, C., Wood, E. and Jabbour, L., 2016. Impact of fetal alcohol exposure on body systems: A systematic review.Birth Defects Research Part C: Embryo Today: Reviews,108(2), pp.174-180. Ward, R.M., Oswald, B.B. and Galante, M., 2016. Prescription stimulant misuse, alcohol abuse, anddisorderedeatingamongcollegestudents.JournalofAlcoholandDrug Education,60(1), p.59. Online Pathophysiology of the Effects of Alcohol Abuse on the Endocrine System.2017. [Online]. Available through: <https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5513689/> How Alcohol Can Impair the Body's Hormone System. 2019. [Online]. Available through: <https://www.verywellmind.com/alcohol-and-hormones-66570> 4