This assignment provides answers to various epidemiology questions including research question, causal diagram, incidence rate, prevalence, cumulative incidence rate, and person-time incident rate.
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Running head: EPIDEMIOLOGY1 Epidemiology Name Institution
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EPIDEMIOLOGY2 Epidemiology Assignment 1 1.Epidemiologists are interested in learning about: All of the above 2.Diseases that are always present in a community, usually at a relatively low constant frequency are classified as having anendemicpattern 3.Which of the following terms best applies to this situation?Epidemic 4.Research Question What is the difference in daily calorie intake between male and female medical students of Northern Ontario School of Medicine? 5.Causal Diagram
EPIDEMIOLOGY3 The exposure in this case is the carbohydrates and the outcome is obesity. When consumption of carbohydrates is high then the chances of being obese also increase. Physical activity is associated with obesity such that engaging in physical activity reduces the risks associated with obesity. Gender is associated with the amount of food consumption which is also related to obesity. Level of carbohydrates intake may also determine the level of physical activity. 6.Temporal relationship means that the exposure must occur before the outcome for causality to be established. 7.Criteria not required to define confounder The confounder is the result of an error 8.Which of the following causes of death is more likely to lead to a higher proportion of years of potential life lost in Canada? Cerebrovascular diseases (stroke) 9.Incidence rate Totalnumberofnewactivecases=2+16+64 ¿82 Person-months of observation¿(250−50)=200 IR=82 200=0.41
EPIDEMIOLOGY4 ¿41per100persons−month 10.Point prevalence numberofcasesatbaseline=50 prevalence=50 250×100 ¿20% 11.Period prevalence totalnumberofcases=82+50=132 prevalence=132 250×100 ¿52.8% 12.What is the exposure of interest? Cancer incidence 13.What is the outcome of interest? Cancer prevalence 14.What is the population being studied? Patients with type 2 Diabetes living in Finland 15.What is the total duration of the period of observation? 16 years
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EPIDEMIOLOGY5 16.Overall hypothesis The presence of type 2 diabetes mellitus increases the chances of having cancer. 17.Incidence rate ¿74063 428326=0.1729 ¿17.3cancercasesper100persons−years 18.For which cancer site does the risk seems higher? Liver 19.Potential confounder The confounder is associated with the exposure of interest. 20.Method used to adjust for confounder Direct standardization 21.Prevalence totalnumberofcases=50 prevalence=50 1000×100 ¿5% 22.Cumulative incidence rate numberofoutcomesofinterest=50+75=125
EPIDEMIOLOGY6 cumulativeincidence=125 1000=0.125 ¿12.5% 23.Person-time incident rate totalnumberofnewcases=75 personyearsofobservation=950×5 ¿4750 incidentrate=75 4750=0.0158 ¿15.8HIVcasesper1000persons−year 24.Why were women who tested positive for HIV excluded from the study population? The reason is due to the fact that they do not meet the inclusion criteria that ensure that subjects are feasible for follow for a prolonged period. 25.True 26.True 27.False