This document discusses the influence of life course on health and well-being, specifically focusing on the stage of mature adulthood. It explores the impact of aging on physical and mental health, as well as the challenges faced by individuals in this stage. The document also highlights the importance of health promotion interventions, with a specific focus on chronic diseases such as diabetes. It provides insights on interventions and strategies to improve health outcomes and prevent the onset of chronic diseases. Overall, it emphasizes the significance of nature, nurture, and culture in promoting a healthy lifespan.