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Evaluating a Quantitative Study on Chlorhexidine Bathing

   

Added on  2020-05-16

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APPENDIX FAppraisal Guide:Findings of a Quantitative StudyAPA Formatted Citation: (4 pts.)Climo, M. W., Yokoe, D. S., Warren, D. K., Perl, T. M., Bolon, M., Herwaldt, L. A., ... & Wong,E. S. (2013). Effect of daily chlorhexidine bathing on hospital-acquired infection.New England Journal of Medicine,368(6), 533-542.Moore, R. A., Gavaghan, D., Tramer, M. R., Collins, S. L., & McQuay, H. J. (1998). Size is everything–large amounts of information are needed to overcome random effects in estimating direction and magnitude of treatment effects.Pain,78(3), 209-216.Synopsis(16 pts.)1.What was the purpose of the study (research questions, purposes, and hypotheses)? The study is meant to discover whether the use of chlorhexidine in patients under specialcare prevents the prevalence of bloodstream infections and Multi-Drug Resistant Organisms.2.How was the sample obtained?Researcher took nine random clusters in either the ICU or bone marrow transplants units of six randomly selected hospitals.3.What inclusion or exclusion criteria were used?Inclusion criteria: the patients included were either in the ICU or the bone marrow transplant units of the six selected hospitals.4.Who from the sample actually participated or contributed data (demographic or clinical profile and dropout rate)?The researcher randomly selected twelve study units; one withdrew while two were eliminated due to low compliance with the study procedure. From the remaining nine uits8patients (0.1%) failed to respond and thus leaving 7727 patients under study. 5.What methods were used to collect data (e.g., sequence, timing, types of data, and measures)?The research randomly assigned units to bath daily using either nonantibacterial washcloths or washcloths treated with 2% chlorhexidine gluconate for six months. The units then alternated the cleaning agents for another period of six months. Acquisition of infection or MDRO was monitored two days after the transition if it occurred during that period.6.Was an intervention tested?Yes A.How was the sample size determined? The clinical isolates in the hospitals under study were selected to form the sample size for testing the intervention.Reproduced with permission from: Brown, S. J. (2018). Evidence-based nursing: The research-practice connection(4th ed.). Burlington, MA: Jones & Bartlett Learning. 1
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