Hyperlipidaemia: Causes, Symptoms, Risk Assessment, and Care Plan

HYPERLIPIDAEMIA

INTRODUCTION
 Hyperlipidaemia refers to elevated levels of lipids
in the blood of an affected person.
 Lipids are nothing but fat proteins present in the
blood.
 But if present in excess causes serious
cardiovascular diseases like heartattack.
 It is also known as Hypercholesterolemia or high
cholesterol.

Diagrammatic representation of clogged
arteries

Genetics of Hyperlipidaemia
 Phenotype of Hyperlipidaemia :
 It is the most common hereditary disorder.
 Leads to coronary death.
 The affected person has high levels of cholesterol or
triglyceride levels.

Prevalence
 1 in 500 people worldwide has familial
hyperlipidemia.
 UK population has the highest level of cholesterol
levels.
 present in one third of American adults
 1 among three sufferers have hyperlipdemia under
control

Details of mutation
 Mutation in LRP6 gene leads to early onset coronary
artery disease and combined hyperlipidemia,
 It causes a cascade of events in diverse signalling
pathways that results in abnormally elevated levels of
LDL and triglycerides