Genre Analysis and Research Assignment PDF
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Added on 2021-06-14
Genre Analysis and Research Assignment PDF
Added on 2021-06-14
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Genre Analysis and Research
Table of ContentsReport.................................................................................................................................3Abstract................................................................................................................................3Introduction..........................................................................................................................3Methodology........................................................................................................................4Study Quality........................................................................................................................5Outline of Results.................................................................................................................4Clinical Significance............................................................................................................5Reflection on learning........................................................................................................6Learning outcomes...............................................................................................................6Critical Analysis / Understanding........................................................................................7References.........................................................................................................................13Appendix...........................................................................................................................142 | Page
ReportAbstractA research article regarding the reproductive epidemiology is reviewed for the understanding of the research methodology and different concepts used in the research study. A research article from the research journal was used for this review. This research study was submitted on February 16, 2016.For this research study, observations are collected from the Centre for Reproductive Medicine of the university hospital UZ Brussels. Data for this research study was collected for the variables such as birth weight, gestational age, prematurity rate, perinatal death, and major/minor total malformation rate. Observations for this research study were collected at different states of research. This study consists of 11 stillborns and 1061 live born babies. In the 1061 live born babies, 827 were singletons and 234 twins. Paediatricians were blinded to the type of embryo transfer. Descriptive statistics and Pearson correlation coefficients were used for all parameters included in this clinical research study for the determination of the different characteristics of the sample. The Chi square test was used for checking the independence between the two categorical variables. A Student’s t-tests were used for checking the significant differences between the population means for the continuous variables. Data is collected for large sample and this will results in getting unbiased observations. The main limitation for this clinical research study is the rather small twin group. So, it is important to interpret the results cautiously for twin group. Due to these reasons, the quality of the research study will be decrease. For most of the statistically tests, 5% level of significance was used for drawing the conclusions. So, results will be significant at 5% level for this research study. All confidence intervals used the 95% confidence level. IntroductionA research study was organized on the reproductive epidemiology in the journal article “Neonatal health including congenital malformation risk of 1072 children born after vitrified embryo transfer” by the authors F. Belva, M. Bonduelle, M. Roelants, G. Verheyen, and L. Van Landuyt. This research study was submitted on February 16, 2016. This study was commissionedfor advance study of artificial methods of human reproduction. These methods are differ than thenatural methods and human interference was performed in the process of human reproduction. This research study mainly focus on the vitrified embryo transfer and the congenital malformation risks of born children by using this method. This study focuses on the research question, “Does vitrification of Day 3 and Day 5 embryos diversely affect the birth outcomes of singletons and twins in comparison with peers born after fresh embryo transfer?” The main purpose of the study is to compare the malformation risk in the children born after vitrified embryo transfer and the children born naturally. Comparably high rates have been reported after 3 | Page
vitrification in comparison with slow freezing methods (Abdelhafez et al., 2010). For this research study, observations are collected from the Centre for Reproductive Medicine of the university hospital UZ Brussels. Data for this research study was collected for the variables such as birth weight, gestational age, prematurity rate, perinatal death, and major/minor total malformation rate. This clinical research study provides the evidence that the transfer of vitrified day 3 and day 5 embryos does not adversely affect the neonatal health of the offspring in comparison with transfer of fresh embryos. For this research study, researchers reports the favourable outcomes for singletons born after transfer of vitrified day 3 and day 5 embryos in terms of different variables such as birth weight, gestational age rate, comparable congenital malformation rate, etc. MethodologyDifferent analysis methods were used for this epidemic study. Systematic study was organized for finding the results for this study. For this study, all study set up and follow up program is already described in the previous publication by Bonduelle et al., 2002. This research study consist of 1072 children and data for these children was collected for the variables such as birth weight, gestational age, prematurity rate, perinatal death, and major/minor total malformation rate. Observations were taken at different time period such as on the time of baby born, day 3, day 5, etc. This study was organized during the year 2008 and 2013 at the Centre for Reproductive Medicine of the university hospital UZ Brussels. Data is collected for large sampleand this will results in getting unbiased observations. If the personnel appointed for data collection is not well educated or skilled, then observations will not be measured accurately and this will results in biased outputs for the study. Also, data is collected between the three to four years. This period for study is comparatively high and even though researchers keeps the proper follow up for the process of data collection at every stage of the research study. This study consists of 11 stillborns and 1061 live born babies. In the 1061 live born babies, 827 were singletons and 234 twins. After the three months of baby births, children were allocated in the two study groups randomly. These two study groups were assessed clinically with special attention regarding the congenital malformations. Single blinding and double blinding techniquesin the clinical study were used for getting unbiased results for this study (Hansen, 2009). Paediatricians were blinded to the type of embryo transfer. Methodology for this analysis is arranged in a systematic way. Two study groups were prepared for this genre analysis and regarding the fresh cycles, analysis of data is restricted to patients who had at least one supernumerary embryo for vitrification. This analysis includes the steps such as ovarian stimulation and IVF-ICSI, evaluation of embryos and selection criteria for transfer and vitrification, follow-up of pregnancy, Preparation of the frozen embryo transfer cycle, outcome measures, and statistical analysis. Paediatricians were blinded to the type of embryo transfer. Cobo et al., (2012) explained the process of blinding in clinical trials. The technique of blinding is used properly for this clinical trial. Data is collected at each stage of the research. Data for 4 | Page
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