This document discusses a clinical case scenario analysis of a patient with a homeostatic disturbance. It explores the symptoms, organs affected, and processes involved in the disturbance. The document also includes references for further reading.
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Health and Homeotstasis 1 (91562) PRC#, Group#: Sneha Khanal, Sunita Sapkota, Srijana Shrestha, Anjali Luitel Poudel ASSESSMENT TASK 1 – CLINICAL CASE SCENARIO ANALYSIS Please delete all red fonts in this template. SET #, CASE 1 – #Diagnosis# (1)In the clinical case scenario, which symptoms (experienced by the patient like chest pain) and signs (observed by another person like swelling or redness) are consistent with the diagnosis? The symptoms which has been mainly associated with the case study is neck pain.The patient is have difficulty in mobility of the neck and also the arms and legs. He is also showing urinary inconsistence. There also has been depression as well as physical dysfunctioning seen (Shier et al. 2015). (2)Given the symptoms and signs in the clinical case scenario, which organs, tissues and/or body parts are involved or affected by the homeostatic disturbance? The main body parts which are affected are the shoulder, chest, arms which are affected by the homeostatic disturbances. There has been compression of the occulomotor nerve on that side of brain which affects pupil the pupil. Moreover the sensory stimuli has been affected as an imaginary line has been drawn across the chest (Sherwood wt al. 2015). (3)What processes are involved that can explain the homeostatic disturbance/s in the clinical case scenario? Spinal cord injury along with spinal infraction have been associated with various neurological complications (Feher et al. 2017). This has ultimately led to paraplegia. An important component of spinal cord injury as the ischemia reperfusion injury which would lead to endothelial dysfunction along with variouschangesinvascularpermeability(Floretal.2015).Alongwith endothelial cell damage spinal cord injury would lead to the ultimate failure in the hemostatic process. Moreover ischemia reperfusion would lead to the triggering of full blown inflammatory cascades which would arise due to innate immune cells. There are two types of injury for spinal cord injury like the mechanical injury along with compression and contusion. Moreover there is thermodynamic instability. The process of commencing of the innate immunity leadstomicrogliaimmunityactivationalongwithstimulatorsneutrophil inactivation. The process of hemodynamic instability would lead to the release of the inflammatory mediators which would lead to the apoptosis of the oligo dendrocytyes. This would be followed by the reduced blood flow along with hemorrhage leading to the initiation of cyst formation along neuropathic pain. Moreover this be followed edema leading to glial scar initiation which would be followed by the destruction of the neural tissues followed by the activation of microglia leading to destruction to neural cell death and neurogenic shock (Lee et al.2014). From the case study it could be seen that the patient would not feel any sensation in the limbs. This would ultimately lead to a misbalance in the
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Health and Homeotstasis 1 (91562) PRC#, Group#: Sneha Khanal, Sunita Sapkota, Srijana Shrestha, Anjali Luitel Poudel homeostatic balance in the body. He would have difficulty in mobility which ultimately added to his increase in pain. There has been generation of pin through various sensory channels which would usually ascend through the homeostatic afferent pathway. Moreover the neural symptoms which has been affected with the spinal cord injury would be connected to various cognitive as well as behavioral processes ultimately leading to disruption in thebasicprocessofhomeostasis.Moreovertheprocessofthereflex sympathetic dystrophy plays an important role in the specific case study as it would be showing various symptoms. There would enhanced swelling and increased pain which would be the main problems associated with the reflex sympathetic dystrophy which would usually occur with patients who would undergo sudden pain due to fear of the various physiological processes and procedures. This excess pain lead to excessive excitation which ultimately affects the homeostatic system (Silva et al. 2017). Inpatientssufferingfromspinalcordinjuries,therewouldbe impairment of the baroreceptor reflex control systems (Singh et al. 2014). Baroreceptors would beresponsible for the maintenance of homeostasis related to blood pressure.This would simultaneously affect the circadian rhythms of the control of blood pressure.Other symptoms affected with the spinal cord injury of the patient are the cases of hypatremia and low plasmatic volume which would affect the postural blood pressure homeostasis (Ma et al. 2014). Although this muscles are showing reflex in the lower extremities, the patient is experiencing numbness due to bilateral ending of sensory stimuli (Anwar et al. 2016). Thus from the following paragraphs it can be seen that there is constant numbness or loss of sensation n in the limbs which would cause an ultimate disruption in the homeostatic balance.
Health and Homeotstasis 1 (91562) PRC#, Group#: Sneha Khanal, Sunita Sapkota, Srijana Shrestha, Anjali Luitel Poudel References Anwar, M.A., Al Shehabi, T.S. and Eid, A.H., 2016. Inflammogenesis of secondary spinal cord injury.Frontiers in cellular neuroscience,10, p.98. Feher, J.J., 2017.Quantitative human physiology: an introduction. Academic press. Flor, H. and Turk, D.C., 2015.Chronic pain: an integrated biobehavioral approach. Lippincott Williams & Wilkins. Lee, B.B., Cripps, R.A., Fitzharris, M. and Wing, P.C., 2014. The global map for traumatic spinal cord injury epidemiology: update 2011, global incidence rate.Spinal cord,52(2), p.110. Ma, V.Y., Chan, L. and Carruthers, K.J., 2014. Incidence, prevalence, costs, and impact on disability of common conditions requiring rehabilitation in the United States:stroke,spinalcordinjury,traumaticbraininjury,multiplesclerosis, osteoarthritis, rheumatoid arthritis, limb loss, and back pain.Archives of physical medicine and rehabilitation,95(5), pp.986-995. Mateják, M., Kulhánek, T., Šilar, J., Privitzer, P., Ježek, F. and Kofránek, J., 2014, March. Physiolibrary-Modelica library for physiology. InProceedings of the 10 th International Modelica Conference; March 10-12; 2014; Lund; Sweden(No. 096, pp. 499-505). Linköping University Electronic Press. Sherwood, L., 2015.Human physiology: from cells to systems. Cengage learning. Shier, D., Butler, J. and Lewis, R., 2015.Hole's essentials of human anatomy & physiology. New York: McGraw-Hill Education. Silva, N.A., Sousa, N., Reis, R.L. and Salgado, A.J., 2014. From basics to clinical: a comprehensive review on spinal cord injury.Progress in neurobiology,114, pp.25- 57. Singh, A., Tetreault, L., Kalsi-Ryan, S., Nouri, A. and Fehlings, M.G., 2014. Global prevalence and incidence of traumatic spinal cord injury.Clinical epidemiology,6, p.309.