The History, Ethics, and Impact of HeLa Cells on Cancer Research

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This essay explores the history, science, and biology of HeLa cells, their uses in cancer research, and their contributions to medical breakthroughs. It also discusses the ethical issues surrounding the use of HeLa cells in biomedical research.

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The history ethics and impact
of HeLa Cells on Cancer
Research

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“The history ethics and impact of HeLa Cells on Cancer Research”
INTRODUCTION
Hella Cells can be understood as immortal cell line used within scientific research,
where it is oldest human cell line and derived from cervical cancer cells. The cells found on 8
February, 1951 from Henrietta lack, 31 year old African American mother who died of
cancer. Essay will discuss details of usage within cell , where it plays crucial role in cancer
research method where tests further has been found to be highly significant essential cell. It is
also found to be also specifically essential where Hella cells are used to study effects of
toxins, drugs and hormones, viruses within growth of cancer cells without experimenting
among humans. Essay will also determine relevant history on data cells, relevant aspects
connected to further determine specific working innovation with changing time period and
also functionally bring keen technical knowledge related to science behind Hella cells
(Rahman, 2021)
Discussion
Hella cells have been found to be highly effective tool, for growing large amounts of
poliovirus, where high amount of virus can be grown in Hela cells that allow scientists to
better understand virus. The high amount of virus has been used within science, biology of
Hella cells where it understands virus which further infects cells and causes diseases further.
The Hella Cells proliferate abnormally rapidly, where it is compared to other cancer cells
where research further has been found to be relevant and essentially forming stronger base for
research within scientific research. It has been also found that immortality significantly
focuses to bring on immortality within its existence, on which it has been critically found to
be having huge history.
Uses, science and biology of HeLa Cells
Scientists discover that Hella cells are fund to be effective tool, for growing large
amount of poliovirus, based on polio disease within beginning where high amount of virus
allows scientist to significantly understand infection caused with virus. Hella cells have
various immortal cell lines, where some of them hold normal cell lines and immortalised cells
which are known to be cancerous cells. Origins of some immortal cell lines are Hella human
cells and are naturally known to be occurring cancers among people (Rahman, 2021). The
Hella Cells have been important for scientific discovery within last century and was the first
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immortal human cell line, which assisted in the treatment of Henrietta by Jhon Hopkins
researcher Dr. George Gey in 1951. Although they were the first cells and multiplied within
lab setting, on which the scientist offered cells freely and widely for scientific research. Over
past recent years, cell line has also contributed within modern biology science to many
medical breakthroughs over research on the effects of zero gravity based on development of
polio and covid-19 vaccines over the study of Leukaemia, AIDS virus and cancer worldwide
treatments. It has also supported significantly over advances within fields of modern research
within recent time period on which cells were further isolated (Xie and et.al, 2021).
Important scientific discoveries of the last century was the first immortal human cell
line, where treatment of cancer has been structured up with huge evolvement in Hella cells.
The scientific usage of Hella cells has been also found to be helpful within treatment of Polio,
improved cell culture practices, chromosome counting which have been considered as three
most major contributions within field of science. Hella cells have also contributed in study of
effects of toxins, drugs where hormones, viruses have been significantly evolving in growth
of cancer cells without experimenting among humans directly. It can be understood that
viruses work, played crucial role for development of new vaccines within advanced medical
science.
In 1952, Hella cells became first human cell that could grow and divide endlessly in
laboratory where it further lead to scientists where cells were found to immortal and highly
essential in specific advanced research in medical treatments (Nott, 2021).
The immortality of cells has continued to have assist in biomedical research among
medicines, and endure usage of Hella cells in biomedical research through significant
timeline of events within researches. It can be analysed that events of research further has
been increased, in more than 110,00 scientific publications rapidly among advanced medical
and biological treatments among research parameters. In 1953, laying ground work for Polio
Vaccine started which has been found to be one of the most significant research within year.
It can be also analysed that within year of 1956, understanding effects of X-rays on human
cells has been also crucial research behind fundamental usage of Hella cells. Further
developing cancer research methods and medical science treatments have been actively found
to be also one of the major contributions by Hella cells where it is highly reliable method in
latest medical science (Yu, Yang and Najafi, 2021).
History and impact of HeLa in treatments
The study of potential treatment benefits of drug called within Hydroxyurea against
blood cancers and cell anaemia, on which it has been found to be applied in cancerous cells
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which also further enabled to slow down their spread. It is also shown within scientific
aspects that Hydroxyurea helps to prevent mis-shaping among red blood cells, which is also
found to be one of the major aspect responsible for sickle cell anaemia (Pourhanifeh and et.al,
2021).
The history of Hella Cells can be understood form year 1951, where Henrietta Lacks,
31-year-old American African women went to hospital for being treated on cervical cancer. It
has been also found useful within research due to specific abilities, for continuous growth and
divide within laboratory. It can be also analysed that immortal cells were later also found as
Hella, which have been named after two initial words of Lady Henrietta Lacks. It has been
also found that untimely death within year 1952, the cells further have been used to create
significant understanding on fundamentals about human health and diseases. Some of the
advanced research involving Hella cells also served as underpinning several Novel prize-
winning discoveries further extended towards advanced medical science.
The significant contribution of Hella Cells has been found to be also strong, where
presence has been identified as major aspect where it further lead to certain cervical cancers.
It has also been found to be achieved Nobel Prize in 2008. The cells are cancerous, which due
to their characteristic to grow fast can be found contaminated and overtake other cell cultures
related with Henrietta Lacks which had syphilis. It has also further resulted within aggressive
growth of cancer due to weakened immune system among humans significantly. Hella Cells
began to compete with cells in developed human immortal cells, which overtook and replaced
cells because of aggressive cancer. Cross contamination has been found to be also
significantly diverse, on diminishing reproducibility of data which is also important to create
validation within findings. This has been also found to be also significant aspect, where
validating findings and data holds huge importance for strengthened vision rise based on
competent pathways diversely (Davenport and et.al, 2021).
Furthermore, advancing understanding of HIV infection, scientists discover that Hela
cells are not infected by HIV where researchers gain significant understanding of infection
works rapidly. The knowledge later also facilitated within drug development, which further
aimed at limiting spread of HIV in body on which Hella Cells have huge history.
National institute of health providers with agreement based on descendants of
Henrietta which allowed biomedical researchers which had controlled access to whole
genome data of Hela Cells. The data of cells have valuable reference tool, where study of

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research behind the fundamental utilisation of developed treatments had further extended
functional rise within authenticity.
The Hela cells has significant importance related to ethical usage where ethics related
to informed consent, privacy and commercialization within collection has been competently
used on. Ethics plays strong role in using Hela Cells, where collection along with storage and
research further developed usage of significant details about informed consent, overnight
large-scale data sharing privacy and confidentiality within usage in medical science. Success
of further utilisation of Hela Cells, depends on acceptability to patients and public, building
and maintaining strong support, trust and transparency within productive scientific usage of
cells. Story of Henrietta Lacks, within creation of Hela cells has been found to be catalyst
within policy changes, based on major regulatory policies among US for informed consent
within biospecimen research further among functional arenas. It reflects on role of Hela
controversy where as per public opinion and general development of biospecimen research
policy, need for informed consent approaches further helped in creating realistic aspirations
fundamentally. Balanced view of autonomy within expanded ethical framework further plays
keen role in analysing functional utilisation towards Hela cells usage in Bio medical research
significantly.
The ethics of using HeLa Cells
Hela cells had significant and lasting impact on huge parameters among ideas, where
areas regarding disease understanding, benefitting millions of patients around world rapidly.
Henrietta Lacks had refused physicians right to collect and use tissues, where contemplating
potential future breakthroughs have hindered data protection resulting power that patient’s
dint had right to use cells in research (Chen and et.al, 2022). The women behind cells
revolutionized usage in medical field helped polio vaccine, and numerous cancer treatments
based on impact of Hela cells, within ethical issues related to informed consent in medical
practices within recent time. The immortal life of Henrietta Lacks focuses on many issues
where, this has been found to be one of the most competent advanced ethical factors crucial
for further extensive research. It has been also identified that ethical issues associated within
usage of Hela cells brought significant public attention about number of ethical issues in
biomedical research within dynamic advanced time period rapidly. It includes role of
informed consent, privacy and commercialisation within collection and usage of
dissemination among biospecimens.
Over the past several decades, cell has been found to be highly influential in medical
breakthroughs and researches which has created significant effect on development of polio
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vaccine, and study of leukaemia, cancer worldwide. There has to be informed decision done
in making productive usage of Hela cells, where it heads on specific focus on extended
potential utilisation of information and opportunity to make informed decision regarding
treatments. It has been found to hold power among transformation in cancer patients, where
early detection and further advancement holds huge importance for analysed growth among
studies for gaining stronger functional knowledge (Al-Oqail and et.al, 2021).
As healthcare providers, there has been found specific responsibility to make sure
patients and families have understood genetic information, offer consent for further vital
usage among treatments. The course of treatment for cancer, specified focus on fact that
doctors within medical science have been able to evolve towards advanced cancer treatments
based on proper ethical usage. There are specific challenges raised about medical samples
which have been found to be taken without consent, which has to be further taken as per
discoveries based on tissues potential usage. Ethical issues have been found to be highly
crucial for strengthening effective utilisation of cells within extended medical advanced
research, where professionals have been stringently evolving. The practical medical usage of
Hela Cells have been potentially done by further extended utilisation of ethical format, and
developing proper synchronized medical usage among new treatments (Aboutalebi,
FTeimouri and Pooladi, 2021).
Conclusion
Essay research has concluded recent findings, where presence of HIV has lead to
varied types of cervical cancer treatments and discovery lead to cervical cancer paves for
development in anti-cancer vaccines specifically. The essay also further shed light on history,
origin of Hela cells form year 1951, by Henrietta Lacks being the founder and lady behind
development of Hela cells. Study also further concluded effective potential contributions of
Hela Cells in research within medical science diversely and to imperatively develop
strengthened vision for extended competitive abilities. Research has also summarized specific
functional aspects connected within advanced medical science, where Hela cells has been
potentially most significant contributed cell among creating vaccines due to immortality.
Essay also vitally developed specific findings connected on technical factors,
determinants specifying worked on rise, where ethical usage of cell has also opened up
research specific paradigms diversely. Study also concluded potential utilisation and
contributions in medical breakthrough, recent research on development of polio. Covid -19
vaccines and study of leukaemia, along with cancer treatments globally.
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REFRENCES
Books and Journals
Aboutalebi, F., Teimouri, M. and Pooladi, M., 2021. Evaluation of cellular and molecular and
anti-apoptotic effects of lipid nanoparticle-containing Artemisia extract in
ovarian cancer cells.
Al-Oqail, M. M. and et.al, , 2021. Oxidative Stress Mediated Cytotoxicity, Cell Cycle
Arrest, and Apoptosis Induced by Rosa damascena in Human Cervical
Cancer HeLa Cells. Oxidative Medicine and Cellular Longevity, 2021.
Chen, L., and et.al, 2022. Molecular engineering of covalent organic frameworks with
elevated mitochondrial-targeting for cancer cell suppression. Sensors and
Actuators B: Chemical, 350, p.130861.
Davenport, V ., and et.al, 2021. An Assessment of InP/ZnS as Potential Anti-Cancer
Therapy: Quantum Dot Treatment Increases Apoptosis in HeLa
Cells. Journal of Nanotheranostics, 2(1), pp.16-32.
Nott, R., 2021. “HeLa Cells 50 Years On: The Good, The Bad, and The Ugly”(2002), by
John R. Masters. Embryo Project Encyclopedia.
Pourhanifeh, M. H., and et.al, 2021. Therapeutic Applications of Curcumin and its Novel
Formulations in the Treatment of Bladder Cancer: A Review of Current
Evidence. Anti-Cancer Agents in Medicinal Chemistry (Formerly Current
Medicinal Chemistry-Anti-Cancer Agents), 21(5), pp.587-596.

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Rahman, M., 2021. The Effect Of Dosage Of Mangrove Leaf Extract Avicennia Marina On
The Viability Of Hela Cells. Journal of Stem Cell Research and Tissue
Engineering, 5(1), pp.41-51.
Rahman, M., 2021. The Effect Of Dosage Of Mangrove Leaf Extract Avicennia Marina On
The Viability Of Hela Cells. Journal of Stem Cell Research and Tissue
Engineering, 5(1), pp.41-51.
Xie, B and et.al, 2021. Hollow and Porous Fe3C-NC Nanoballoons Nanozymes for Cancer
Cell H2O2 Detection. Sensors and Actuators B: Chemical, 347, p.130597.
Yu, C., Yang, B. and Najafi, M., 2021. Targeting of cancer cell death mechanisms by
curcumin: Implications to cancer therapy. Basic & Clinical Pharmacology &
Toxicology.
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