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HLT1RAE Research & Evidence In Practice

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Australian Catholic University

   

Research & Evidence in Practice (HLT1RAE)

   

Added on  2020-02-24

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This is descriptive research that uses both quantitative and qualitative methods. The researchers wanted to see how Garcinia Cambogia medication affects weight gain or loss in obese women. The researchers gave sufficient introductory statements to provide the context for their investigation.

HLT1RAE Research & Evidence In Practice

   

Australian Catholic University

   

Research & Evidence in Practice (HLT1RAE)

   Added on 2020-02-24

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Running head: EVIDENCE APPRAISAL1Evidence AppraisalNameAffiliation
HLT1RAE Research & Evidence In Practice_1
EVIDENCE APPRAISAL 2Summary of nature, aims, and hypotheses of the studyThis is an explanatory study with both quantitative approach and qualitative approaches. The investigators sought to establish how treatment with Garcinia cambogia affected weight gain or reduction in obese women. The researchers provided adequate introductory statements to build background for their study. They provided a widely accepted definition of ‘obesity’ as an excess accretion of body fat following a disparity of caloric intake and use coupled with reduced physical activity. They also provided a linkage of obesity to metabolic conditions including dyslipidemia and type two diabetes. This is commendable because it shows adequate justificationof the study. The study’s attempt to link obesity and its comorbidities including insulin and adipokines are significant because endogenous processes of homeostasis are integral to energy use in the body and the consequent build of fat, or lack thereof. Vasques et al. (2014) aimed to study the clinical efficacy of the medication with the extract of G.cambogia with respect to enhancement of anthropometric and metabolic factors women with obesity, in addition to analyzing its effect on leptin amounts. The aim supports the fact that very few past scientists have conducted evaluations on the proficiency of ability of G. cambogia to augment lipid profile or its consequent effect on leptin quantities in humans. Similarly, most paststudies concentrated on evaluating Garcinia cambogia affect weight reduction in animals unlike the current study which targets humans as study subjects. Anchored in the aim, the study hypothesized that there is a relationship between amounts of leptin and metabolic adjustments in human and animals. It was also hypothesized that hypolipemic effect as a result of the treatment with garcinia extract has a strong relationship withleptin secretion induced changes.
HLT1RAE Research & Evidence In Practice_2
EVIDENCE APPRAISAL 3Summary of methods used in the studyThe study recruited 60 obese women in the Novo Hamburgo City. The completion rate of the trials was acceptable because 43 women did, representing 71.7 % of the total study participants. All study participants met the study criteria which included stability of eating habits, not followers of low-energy diet and stability of body weight in a period of three months. Additional inclusion criteria included stability of physical activity, no use of drugs known to cause weight gain, good appetite, similar glucose and lipid profile and generally good health. Women with a history of smoking and alcohol and drug abuse were excluded from the study as those with cancer, diabetes type II, history of endocrine abnormalities and bulimia. Creatinine of 75–115 mL/min, phosphates of 300 U/I and TSH levels ranging between 0.3 and 5.0 μUI/mL were also taken into account. With the admission and exclusion criteria, the investigators made sure that allstudy participants were near uniform to avoid outlier results. The investigators used a double blind randomized study design in evaluating the pharmacotherapeutic efficiency of two months of treatment with day-to-day dosages of G. cambogia uniform extract (2.4 g/d). Use of randomized study was important because it preventedthe study outcomes from ' inspired’ by the placebo effect. It made sure that the treatment group comprising of half the study population was unaware of what the remaining half was having. Random sampling applied to isolate the experimental group from the control group was instrumental in obtaining a representative half in either group. The daily caloric intake of the women was assessed (1903 ±453 kcal/d) after which an individualized meal plan is providing 1523 ±185 kcal/d was given to each. Upon finishing the month treatment plan, various parameters including anthropometry, lipid profile, serum insulin, leptin and resting energy expenditure were assessed. Patient’s dietary intake was also assessed before and after treatment
HLT1RAE Research & Evidence In Practice_3

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