Hormonal Control of Reproduction: Anatomy, Gamete Development, and Conception
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This report discusses the anatomy of male & female reproductive systems, how hormones control gametogenesis, the stages of menstrual cycle, and the role of hormones in conception. It also evaluates how conception can be prevented and promoted.
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Hormonal Control of Reproduction 1
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Contents INTRODUCTION.....................................................................................................................3 TASK........................................................................................................................................3 P3 Describe the structure and function of reproductive anatomy.........................................3 P4 Describe how hormones are involved in gamete development and conception..............8 M3 Explain how development of male and female reproductive system can affect male and female reproductive health..................................................................................................12 D3 Evaluate how conception can be prevented and promoted............................................14 CONCLUSION........................................................................................................................15 2
INTRODUCTION Human regulation is defined the ability of organism’s that keep remain constant the internal environment. Homeostasis is the most important characteristic in order to improve the living style of human body. The report will discuss the anatomy of male & female reproductive systems, using annotate diagrams description of how each part functions. The reproductive systems are applied in the report to control or manage by FSH, stands for gonadotropins follicle stimulating hormones. By using labelled diagrams, it will explain that how hormones control gametogenesis in terms of females and males. Furthermore, it will produce labelled diagram, identify the different stages of menstrual cycle and understanding the actions involves in controlling the cycle. However, it will identify the normal regulation in regards of male fertility. TASK P3 Describe the structure and function of reproductive anatomy The Male Reproductive System- It is situated in the outside of human body. It should be covered the external organs such as testicles, penis and scrotum. Male reproductive system is one of the responsible part in terms of sexual function and urination. Figure: 1 Anatomy The Root- It is main part of penis that attached to the wall of abdomen. 3
The Shaft – it shows the shaped such as cylinder, tube. It has been developed by three chamber. In the internal, it has made up erectile tissues that should contain large amount of spaces. It has been filled with blood. The glans – it is also representing the cone shaped end and also known as penis head. It is covered with layer of skin and removed in the specific procedure. Functions The function of male reproductive system is dependent on the hormones. It will be released the chemicals that stimulate or regulate the activity of organs, cells. Initially, the primary hormones are performed the functioning of male reproductive system such as luteinizing (LH), follicle-stimulating hormone (FSH). These kind of hormones are produced with the help of pituitary gland. It also managed and control the brain functionality and responsible for handling entire body functions. FSH can be produced the sperm production and LH stimulates the production of testosterone. Testosterone is helping the development of characteristics of male. The Female Reproductive System – It is defined the series of organs which is primarily located inside the body and situated in the pelvic regions. It consists of three important parts- vagina and also lead from vulva, opening of vaginal. Usually, it has been identified that vagina is directly meets the outside a vulva. In order to perform different functions while releasing the lubricants. On the other hand, it has been identified that ova can be fertilized because of sperm. After few months, it does not happen a fertilization and also linked with uterus. 4
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Figure: 2 Anatomy Labia majora – it is main part of female reproductive system which enclose and protect the external organs. Ovaries- it represents the oval shaped glands that are majorly located on the one sided. Uterus- it has been shown a pear shaped organ and also developing fetus. Uterus can be categorised into different ways: - Cervix and corpus. Bartholin’s glands- it has been situated in the next of vaginal opening on every side. It produced a fluid of secretion. Clitoris- it consists of two labia minora and meet at the clitoris. A small division of sensitive protrusion which has been compared to the males. It should be covered by skin fold and also known as prepuce. 5
Functions In this section, it has been identified the function of female reproductive system which produce and sustain sex cells such as eggs, ova. These kind of cells are performing the different role in order to transport in site where it would be increased the possibility of fertilization by sperm. It also creating a suitable environment so it easily developing fetus. In some cases, it is also moving towards outside of development period. Structure for female reproductive anatomy Description of function. Structure for male reproductive anatomy Description of function. OvaryToproduce&store eggsandtomake hormones EpididymisTheirfunctionisto transportspermin male body from rete testes to vas deferens. Fallopian TubeTheirfunctionisto transportoocyteand fertilize. Seminal vesicleTomakesugarrich fluid that may provide sperm with a power of energy. UterusTonourishthe productionoffetus prior to birth. Couper's glandThe function of this male body part is to presentinferiorto prostate gland in male reproductive system. FimbriaeTo enable bacteria to bindtoparticular receptor structure. Prostate GlandTo produce fluid that transportandalso nourishesseminal fluid. EndometriumThe main function of thispartin reproductive system. TestesTheirfunctionisto makespermand include in production of testosterone. CervixToprotectPenisTo sexual intercourse 6
reproductiveorgans infemalefrom infectionofviruses and bacteria's. and urination. VaginaTochannelsperiod bloodoutsideof female body. ScrotumTheir function is hold testiclesandvaried nerves. LabiaThe function of this partistoprevent opening of vagina and urethra. Vas Deferens Wafting of ova through fallopian tubes- Fallopian tube may transport eggs in female body from ovary to uterus, and each egg may pick up through out fimbriae and then swept toward uterus. This process is directed by beating cilia and peristalsis which is rhythmic contraction of muscles. Fertilization- This term refers to union of two haploid gametes such as spermatozoa and occyte, whichhelptorestorediploidstate.Acrosomereactionthatmayoccuraftersperm capacitation. It may play significant role during the process of fertilisation in term of making spermatozoa capable or effective to penetrate zone and also able to fusing with egg plasma membrane. Implantation- The process of fertilization encompasses current term as well which is quite important to achieve the pregnancy. It is fact that without implantation the blastocyst can be break down and expelled with other of uterine lining during time period. Role of hormones- Hormones helps to coordinate human body functions such as fertilisation in female from metabolism to progress and develop, emotions, sexual function, etc. Testosterone, estrogen and progesterone are three different types of reproductive hormones that plays 7
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important role in fertilization or fertility, and are produce in ovaries in female and testes in males. Spermatogenesis from spermatogonia- It is a kind of procedure by which haploid spermatozoa grow from germ cell within seminiferous tubules of testis. It begins with mitotic segregation of stem cells that may locate near to basement membrane of tubules, which known as spermatogonial stem cells. Formulation of primary and secondary spermatocytes and spermatids- Primary spermatocytes called diploid cells and formed after meiosis and are also haploid cells that encompasses half number of chromosomes. The secondary spermatocytes and spermatids are formed last long than 2 weeks and contain a haploid complement of 1N such as chromosomes. Role of Sertoli and Leydig cells- Sertoli cells role is to test formulation and spermatogenesis in term of facilitating growth of germ cells. Whileleydigcellsroleistodevelopspermproductionandcontrolsexual development in the body. P4 Describe how hormones are involved in gamete development and conception FSH is kind of hormones which act as gamete-producing the cells and regulate the level of gametogenesis. On the other hand, LH behave as endocrine, producing the hormones cells. It is helping to stimulate the steroid, assume as sex hormones. These are helping to check the level of producing cells and also controlled over production of sex hormones. The reproductive systems are used the sexes and helps to share kind of enterprise. For example- the gonads has produced the gametes like sperm & eggs, united at the time of fertilization. Whenever it has produced the level of steroid hormones which plays an essential role in the reproduction. The genitalia is becoming consider as an external reproductive structures such as clitoris, vulva in females and penis in the males. These are allows to transmit the sperm from male to female. As identifying the gametes creation which is also known as gametogenesis. It has been following the process and maintain a sequence in both cases such as male and female. On the basis of analysis, Gamete started to the germ cells and 8
develop and also multiplying the embryo. It contained with 23 different pairs and showing total 46 chromosomes. It can be occurred through mitosis. In the context of female reproductive system, it has been produced the progesterone, estrogenhormones.Themainaspectofthesehormonestodevelopormaintain characteristic’s level of female reproductive system. Figure: 3 In Female reproductive systems, progesterone as well as estradiol are the useful steroid hormones. It helps to prepare the entire body for purpose of pregnancy. In case of estradiol, it is always produced the secondary characteristics in female while regulating the cycle of menstrual. By using FSH and LH, the pituitary glands associated with the portion of anterior and supports to produce the prolactin hormones (PRL). The level of prolactin has been stimulating the level of production of milk through mammary glands. Apart from that, it is also regulating the prolactin with the help of prolactin releasing hormones. The posterior releases the hormones of oxytocin which stimulates the contraction in the uterine at the time of child-birth. In the context of male reproduction,it has been suggested that usesLH, FSH hormones and always supports the spermatogenesis process. The role of these two terms isto help establishment of connection or signals from one node to another. Thus, it is promoting the importance of spermatogenic cells. In some situation, It can be produced the hormones while using the sertolic cells. In order to concern about the female and male reproductive 9
systems. It is capable of producing enough level of hormones like estradiol, inhibin. This kind of hormone is capable to produce the high level of estradiol. Additionally, it including the enough testosterone so that it can be managed or controlled the role of hormones. In male body, LH role is to make testosterone that is essential for production systems. Furthermore, FSH also plays significant role in male body in term of controlling the production of speum. On the basis discussion, it has been summarised the concept of both female and male reproductive systems. It focuses on the gonadotropins FSH and LH hormones, and also produced with the help of pituitary gland. Gonadotropin will be released as control or handle by hypothalamic hormones. It is also stimulating the level of maturation of cells in the female or male. The major role of oestrogens’ are producing the steroid hormones and automatically triggered the development of characteristics of sex. On the other hand, it should be used the Leydig cells which produced or maintained the testosterone. It regulates to the both female and male reproductive system. Generally, it can be categorised into different groups- menstrual cycle as well as ovarian cycle. It occurs the Menopause when it loses the ovaries because of sensitive hormones like FSH, LH. Producing a graphical representation to describe the stages of menstrual cycle and actions of hormones included in controlling the cycle. Menstrual cycle is defined as monthly procedure and series of common changes in a female body that goes via in preparation for possibility of pregnancy. This cycle encompasses different stages and these are; Menstrual phase- This stage usually lasts from day 1 to 5, which define the time when lining of uterus is mostly shed out via vagina, when pregnancy among female has not occurred. It can be said that most of the female's bleed during this time duration from day one to 5, but a time lasting only two days to as more than seven days is still recognized normal. Follicular phase- The second phase of menstrual cycle may begin in term of lowering the extent of progesterone and estrogen. As an outcome, the top-level of thickened lining of endometrium break down and are outbuilding as well as menstrual bleeding happens. About this duration, folliclestimulatinghormoneextentincreaseslightlyandstimulatingtheformationof contains an egg. 10
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Ovulation phase- It can be said that the third stage of menstrual cycle may begin with a surge in masculinizing hormone and follicle stimulant hormone extents. These essential hormone may support to stimulate the egg which mostly occurs 16 to 32 hours after flow begin. The steroid hormone extent may decrease at the time of surge and progesterone level begins to increase more than that. Luteal phase- The current term is also included in category of menstrual cycle phases, which may begin after ovulation. This stage may need only 14 days and end just before a menstrual time, that help to move overall procedure toward further outcomes. The ruptured follicle in the last phase of overall cycle has closed after releasing egg in female body and form specify structure named a corpus luteum. Actions of hormones involved in controlling menstrual cycle- Progesterone and estrogen, are the two types of hormones included in menstrual cycle and support to control the overall cycle in appropriate manner. Progesterone may prepare the female body for pregnancy in releasing the egg that is fertilized. When the egg is not fertilized, then corpus luteum may break down and the overall production of current hormone fall that outcome in form of forming new menstrual-cycle. The main action of progesterone is to support continuous the cycle and get uterus ready to accept the situation that is called pregnancy. Like progesterone, estrogen as another hormone support to control the entire cycle during luteal phase, where extent of this element is high. Normal regulation of male fertility- CFTR is the main regulator of male fertility that is considered as a defect of that outcome in varied forms of male fertility other than congenital absence of vas deferens. The cystic fibrosis transmembrane conductance regulatory is a CAMP activated HCO3 and CI conducting sources, mutation of which are named to be connected with male infertility. Increasing mutation frequency or elimination of CFTR express in male with congenital bilateral absence of CBAVD. This term may cause by low sperm development and abnormal sperm action that may prevent the delivery process of sperm from male to female body. Chronic health issues, illnesses, and other factors contributes to male infertility. 11
In menstrual-cycle the female body discards monthly build up of lining of uterus or womb. The average length of menstrual-cycle is 28 to 29 days, but it may vary between female and from one cycle to the next. Oogenesis from oogonia- In human body oogenesis occurs in external most layer of ovaries in male, which begin with a germ cell names oogonium. Formulation of primary, secondary and graafian follicies- In menstrual-cycle when primordial follicle is stimulate it may outcome in term of primary follicle and when activate the first meiotic division is complete it may result in form of secondary and graafian follicies. Role of Corpus luteum- The role of corpus luteum is to make uterus a good place for a fetus to develop. It supports to release a hormone name progesterone that make uterus able to keep duration pregnancy. M3 Explain how development of male and female reproductive system can affect male and female reproductive health The health of males and females is affected because of reproductive development. GnRH stimulates pituitary gland in order to produce follicle stimulating hormone. The hormone is mainly responsible for starting the follicle development and creating the level of Estrogen which is primary female hormone in order to rise. Testosterone mainly stimulates the sperm production in the male. These hormonal changes affect the health of males and females. There are many ways in which reproductive health of individuals can be affected because of reproductive system and can result in infertility. These are defined below: Meiosis during gametogenesis The procedure of the meiosis is mainly responsible for the gamete formation that ensures offspring is being inherit the complete set of chromosomes from each of the parent. The errors that has been arrived due to this process is generally results in the abortions, infertility and birth defects. While meiosis produce gametes with the extra and missing chromosomes than this results in that fertilisation in which the chromosomes are affected. Often, in this case the embryo is not viable. However, some of these errors can lead to 12
trisomy conditions and sex chromosome disorder.As a result, this leads to develop infertility. Thus, major two errors either the part of chromosomes are attached to each other or the part of chromosomes in completely missing. These errors impacts meiosis during gametogenesis and develops the infertility. Obstruction of male and female tubules The tubal factor infertility mainly occurs when the blockage under the fallopian tubes nor allow egg and sperms to meet. The tubal factors infertility has been mainly witnessed about 25-35% in all the cases of infertility. The major conditions are associated with the blocked fallopian tubes and other cases in which only one is blocked tube and scarring narrow to the tubes. The major causes of tubal factor infertility are the endometriosis. It can causethescarringinbetweentheendiffallopiantubeandovary.Chlamydia andGonorrheahas been determined as the commonly sexually transmitted infections that might often cause infertility. In male, damage that occurs in reproductive system leads to cause low or no sperm. Male who are facing azzospermia are concerned with the blockage in the tube where the sperms travel. Hormonal control of egg\sperm development Ovulation can be disturbed due to the changes occurs in the ways in which certain hormones has been released from hypothalamus. (Part of the brain that releases GnRH and the pituitary gland and FSH). Thus, Backward movement of the sperm in the bladder instead of getting out through the penis causes the infertility.In rare cases, infertility results from the hormone deficiency. When the GnRH and Gonadotropin hormone in female and FSH and LH in men gets disturbed then, it leads to impact the development of egg and sperms that further causes the situation of infertility. Development of zygote ZIFT refers to the zygote intra-fallopian transfer. It refers to the fertility treatment that has is assisted reproductive process that is similar to the vitro fertilization and the ebryo transfer. In this, embryo has been transferred with the help of fallopian tube rather than uterus. During the process of fertilization, the egg and sperms unite in one fallopian tube in order to form zygote. Afterwards, zygote travels from the fallopian tube in which it becomes the morula. When zygote reaches the uterus then the morula become blastocyst and then it 13
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forms in the uterus lining. The abnormal development of zygote leads to development of infertility. D3 Evaluate how conception can be prevented and promoted Hormonal method for preventing and managing conception contains the Estrogen ir the progestin only as it has been considered as the safe and reliable method for managing and preventing fertility. The different method if hormonal controls includes: Artificial insemination- It is one of those effective methods that utilize in term of treating infertility by inserting semen into a womb in female body. It may work in term of letting sperm skip cervical mucus totally. It may put positive impact in term of preventing sexual transmit disease, which falls under the category of their key strength. While it may also encompasses some disadvantages such as require well trained operations and specific equipments. IVF- In Vitro Fertilization is also utilized to prevent and manage fertility, in term of affecting the overall process positively. The strength of this approach is that it help to prevent genetic issues and also support in the context of conception of a child. Birth defects and cancer are the weaknesses of IVF approach. Induction of ovulation- This methods is utilize for purpose of stimulating egg development or production and also release the same. There are some strengths and weaknesses of current technique accessible, such as it helps to simulate development of egg, but also become a reason of breath loss, blurry vision, hot flashes, etc. HRT- Hormone Therapy is used to replenish low extent of female hormones and also to consider the impact of menopause. It may influence the thickness of uterus lining that may affect whether a fertilization of egg in the female body or not. It may help to reduce the fertility, which is one of their strengths, but also impact negatively because of having weaknesses and these are a person feel sick, leg cramps feeling and bloating as well. 14
CONCLUSION On the basis of above discussion, it has been concluded that male and female reproduction systems has supported by several factors that exist in the body of both candidates. The hormones have appropriately controlled gametogenesis in male and females that in turn provided desire outcomes to both. Furthermore, from above analysis, it has been identified that each phase of menstrual-cycle has contributed to fertilized egg and make a woman pregnant. All the four stages of this cycle encompasses some specific and essential actions that in turn provide the desire outcomes. Along with above consideration and information, it has been determined that progesterone and estrogen, hormones are supported to make appropriate and essential controlled over menstrual-cycle. 15