This article examines the role of Human Resource Management (HRM) in the healthcare sector, focusing on its impact on management practices and employee well-being. It analyzes the evolution of HRM in healthcare, compares practices in different countries, and discusses the challenges and opportunities for improvement. The article also explores the importance of effective employee management relationships and the role of HRM in reducing burnout among nurses. Overall, it highlights the significance of HRM in enhancing the quality of healthcare management.