Intestinal Lymphoma - Symptoms, Diagnosis and Treatment

Running Head: INTESTINAL LYMPHOMA
Intestinal Lymphoma
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INTESTINAL LYMPHOMA
Abstract
According to Ferreri, Zinzani, Govi, & Pileri, (2011) gastrointestinal tract lymphomas are
very rare menacing disordesr that accounts for only 1-5% of the total gastrointestinal tract
malignancies. The most common type is lymphoma of B –cell origin but, there are rare cases
of the peripheral T- cell lymphomas of the ileum that has been reported so far (Carrasco et
al., 2015). Gastrointestinal lymphoma is the most prevalent to attack from non- Hodgkin’s
lymphoma. Colon and rectum are not commonly involved when compared with stomach and
very small bowel (Hoshikawa, Takagi, Koike, Maeda, & Tadokoro, 2004).
Introduction
The digestive track lymphoma of the bowel is not common as compared with
adenocarcinoma, signet ring lymphoma is very rare variant of non- Hodgkin’s lymphoma
(Elli, Contiero, Tagliabue, Tomba, & Bardella, 2012)). The disease is characterised by the
occurrence of the presence of clear cytoplasm that instead they replace the nucleus to the cell
periphery thus, giving the cell an appearance of signet ring. Primary intestinal lymphoma is
not very common and comprises of 0.2% -0.65% of the all known colic malignancies (Kiupel
et al., 2011).
Basir, Bickle, Telisinghe, Abdullah & Chong, ((2012) explains most of these tumours
are composed of b-cells, but study has also shown that t- cell lymphoma of the small intestine
is secondary to a celiac condition. Intestinal lymphomas are divided into various entropathy,
T-cell lymphoma (EATCL), EATCL lymphoma that don’t have enteropathy and the non-
EATCL (Vaidy et al., 2013).
EATCL manifests itself as multifocal with circumferential ulcers that is located near
the jejunum. This type of lymphoma is always associated with history celiac disease and

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shows tumours cells that are CD4-, CD5-, and CD7+,CD8-/+,CD3+and CD103+7. It has also
been confirmed that all ATLL that is associated with retrovirus has not been documented
(Gou, Zang, Jiang, Yang, Cao & Chen, 2012).
Case study
A 21yearold male was presented having ileac lesions for more than 9 months and
currently found blood in stool after drinking alcohol and eating sea food for about 1800g, and
had transient black sputum for several seconds no syncope and loss of consciousness. For the
past the family said that he had a history of blood in the stool at age of one year which
improved after no special treatment. The symptoms were detected after taking alcohol and
eating sea food.
Physical examination revealed that the young man is clear minded and self-subjected.
The general conditions were not high temperature (36.1o), stable blood pressure (140/90
mmHg), weight 73kg, height 170 cm and acceptable sleep. He had no distortion of the thorax,
no tenderness in the sternum, the heart rhythm regular with heart beats being 101 beats /min.
he had no significant change in the body weight, normal bowel movement, no touch under
the liver and spleen, murphy’s sign(-).

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Figure 1 Auxiliary examination 2017-4-17 gastroscopy showing: chronic non-collapse
gastritis, pathological results showed: (gastric biopsy) mucosal chronic active inflammation
with erosion. (Shandong Provincial Hospital) 2017-5-25 colonoscopy).
The bowel sounds were normal and had no lower extremity edema, gastroscopy was
carried out and showed chronic non –atrophic gastritis, and pathological showed that mucosal
chronic active inflammation with erosion (gastric biopsy) from Shandong provincial hospital.
Auxiliary examination showed no significant abnormalities in the colorectal and capsule
endoscopy showed there was no obvious ulcer occupying and there was active bleeding in the
lower part of small intestine from Qianfoshan hospital.