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Hypothesis Testing Examples for Medical Research

Conduct a study to compare means of three groups, each getting one of three statin drugs to reduce cholesterol using one-way ANOVA with Tukey follow-up for pairwise differences.

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Added on  2023-05-30

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This article discusses three examples of hypothesis testing in medical research. The first example explores whether doing yoga regularly can lead to lower blood pressure. The second example investigates whether blood pressure levels are linked to altitude and age. The third example tests a new drug's effectiveness in preventing migraines. Each example presents the null and alternative hypotheses, independent and outcome variables, and the method used for testing. The article concludes with the results and conclusions drawn from each example.

Hypothesis Testing Examples for Medical Research

Conduct a study to compare means of three groups, each getting one of three statin drugs to reduce cholesterol using one-way ANOVA with Tukey follow-up for pairwise differences.

   Added on 2023-05-30

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Example 1
I want to check whether doing yoga regularly can lead to lower BP or not. Two groups are
selected and one of these groups does yoga for 1 hour daily while the other group does not.
1) Present your null and alternative hypotheses
H0: μ1= μ2 i.e. no difference in the mean BP between the two groups
H1: μ1< μ2 i.e. the group doing Yoga has a mean BP lower than the other group not doing
Yoga.
2) Define your independent and outcome variables
Independent Variable: Exposure to Yoga or not
Outcome variable: Blood Pressure
3) Indicate the method you will use and why you will use it
Two independent sample t test would be used. Since population deviation is not known,
hence t statistic would be used. The two sample are independent and have numerical values.
4. Assume your result will be statistically significant and what your conclusions will be since
it is
H0 is rejected and alternative hypothesis is accepted. As a result, it can be concluded that
Yoga is indeed effective in reduction of blood pressure in significant manner.
Example 2
I want to check if the mean blood pressure level of individuals is linked to the altitude at
which they stay and their age. As a result, the data for 200 people has been collected.
1) Present your null and alternative hypotheses
H0: β1= β2 = 0 i.e. each of the two slopes is insignificant and hence can be assumed to be zero.
H1: Atleast one of the slopes is significant and hence non-zero.
2) Define your independent and outcome variables
Independent Variable: Altitude, Age
Outcome variable: Blood Pressure
Hypothesis Testing Examples for Medical Research_1

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