Effectiveness of Strict Glucose Control on Diabetic Neuropathy: A Meta-Analysis

Running head: META-ANALYSIS
Meta-analysis
Name of the Student
Name of the University
Author note

1META-ANALYSIS
Introduction:
There are many studies that claim that strict Glycemic level can prevent and delay the
comorbidity of diabetic retinopathy, neuropathy and nephropathy. The objective of this meta-
analysis is to examine the effectiveness of strict glucose control on diabetic neuropathy through
reviewing multiple literatures.
Data extraction:
Search Terms:
The terms that have been used for the literature searching are Glucose Control, Diabetic
Neuropathy and Strict Glycamic Control, Type 2 diabetes, Type 1 diabetes. Several combination
of these search terms have been also used while utilizing special characters for searching. These
special characters are ‘term 1+term2’, ‘term – excluded term’, ‘ ”terms” ’and others.
Databases.
Database is the digital library from which the research articles could be searched and
selected. The entire data collection has been done through Google Scholar or
scholar.google.com, PubMed, NCBI (National Center for Biotechnology Information Search
database) library or ncbi.nlm.nih.gov and BMC or biomedcentral.com.
Study Selection Criteria
In this Meta-analysis study the selection criteria is based on two sets of criteria, namely
the inclusive criteria and the exclusive criteria. The inclusive criteria for this Meta-analysis were
RCT (randomized control trial) intervention, measurement of DPN and CAN, Experimental
study with interventions, Type 1 diabetes, Type 2 diabetes. On the other hand, the exclusion

2META-ANALYSIS
criteria were non-experimental study, Quasi-Experimental Study, HbA1c measure focused study.
Initially, 12 studies were selected and after filtering through inclusion and exclusion criteria 4
studies have been chosen. Two studies have been selected to measure the intervention process
for Type 1 diabetes patients and two studies have been selected for Type 2 diabetes patients.
PRISMA 2009 Flow Diagram