NGS Technology: Enhancing Understanding of Breast Cancer

NGS TECHNOLOGY
How has NGS technology Enhanced our understanding on Breast Cancer
Student’s Name
Institutional Affiliation

NGS has promoted our knowledge
regarding the new breast cancer cells
 NGS technology has through the sequencing of breast growths has
exposed the presence of new breast cancer cells
 Though the genes are not regularly mutated, the mutated genetic
factors from diverse patients are convened into deregulation of
comparable pathways.

NGS has revealed alteration in the
somatic cells in the breast cancer genome
 By sequencing the germline DNA together with tumor, the technology
may expose somatic gene alteration in the breast cancer genome.
 The variations in somatic genes can be classified into two.
 First, the changes can be classified according to their role in the
disease, as a passenger or driver mutation. Driver mutations results
into the development of breast cancer tumors (Rajendran and Deng,
2017).
 secondly, the somatic cells might be classified as a product of
genomic instability of the tumor.