This study explores the challenges faced by nurses in preventing pressure ulcers in UK healthcare settings. The study is divided into three themes: workplace context, organization in healthcare settings, and implementation of prevention of pressure ulcers. The workplace context includes challenges such as staff shortage, increased workload, patient attributes, models of care, and clinical skills and knowledge. The organization in healthcare settings includes guidelines and equipment maintenance. Implementation of prevention of pressure ulcers includes teamwork, education, and communication and documentation.