This research article explores the failure of peripheral intravenous catheters (PIC) and the use of skin glue as an intervention. The study examines the effectiveness of skin glue in minimizing the failure rate of PICs after 48 hours. The findings show a 10% reduction in failure rate and suggest that the use of skin glue can be beneficial in clinical nursing practice. The article provides insights into the research design, sample, data collection, and analysis. It also discusses the relevance of the study to nursing practice and its alignment with existing evidence.