NURSING AND HEALTHCARE ASSIGNMENT.

Running head: NURSING ASSIGNMENT
NURSING ASSIGNMENT
Name of the Student:
Name of the University:
Author note:

NURSING ASSIGNMENT1
Article 1:
According Bouadma, Karpanen & Elliott (2018), Chlorhexidine (CHG) is considered
as the primary choice within the healthcare setting to prevent or reduce the healthcare
associated infections and bear the anti-microbial property. 0.5% of CHG mixed with the
alcohol is considered as the most effective antiseptic that preparing and cleaning the skin
before any invasive procedure of the patient. The research project was conducted to test for
the efficiency of CHG mixed with alcohol for cleaning the skin of the patient before any
invasive procedure.
From the clinical evidence it was suggested that 2% of CGH was mixed with 70% of
the isopropyl alcohol that will act as the skin antiseptic before the short-term arterial,
haemodialysis and central catheters within the patients admitted in ICU on order to reduces
the threat of catheter-associated contamination as compared to the ≤0.5% (w/v) CHG or
povidone-iodine mixed in alcohol. From the result, it is clear that CGH associated and mixed
with alcohol can be used appropriately for every type of skin cleaning before the invasive
procedure in the ICU. The result were positive for the patient who were practicing the use
CGH in the ICU for the preventing any bacterial infection during invasive procedure.
It can be concluded that CGH has extensive antimicrobial activity and also has large
clinical application that is supported with strong evidences to prevent the onset of bacterial
infection before conducting any invasive procedures.
Article 2:
Girard, Comby & Jacques (2012), performed a primary examination that aimed to
recognize the superior antiseptic agents for preventing the central venous catheter (CVC)-
associated infections for the patient admitted to the Intensive care unit (ICU). The researcher
has used different parameters for comparison such as comfort of use, cost and effectiveness

NURSING ASSIGNMENT2
of the antiseptic agents. The antiseptic agents considered in this study for comparison were
alcohol-based povidone-iodine solution (PVP-IA) and chlorhexidine antiseptic solution
(CBA).
The questionnaire approach was used for identifying and obtaining the result of best
antiseptic agents based on the measurement of CVC infection and colonization frequency for
both PVP-IA and for CBA. The questionnaire list consisted of different question and were
submitted to various hospital pharmacy for understanding and identifying which antiseptics
were best for reducing central venous catheter (CVC)-associated contaminations. This study
has incorporated 806 central venous catheter (CVC).
The result exhibited that switching from alcohol-based povidone-iodine solution
(PVP-IA) to chlorhexidine antiseptic solution (CBA) resulted in significant reduction of
colonization conducted frequency/100 catheter, non-significant reduction of the CVC-
associated bacteraemia/100 catheter days and non-significant reduction concerned with the
CVC-related infection incidence/100 catheter days. The patient provided with PVP-IA were
under enhanced risk of obtaining infection or CVC colonization according to the multivariate
Cox model investigation. Therefore, from this research study, it was evident that CBA were
not recommended for preventing CVC infection due to their reduced cleansing activity.
Article 3:
Fraser et al. (2018), conducted a detail study to examine which prevention strategy
will be beneficial and helpful for preventing the risk of central venous catheters (CVC)-
associated infection in the neonatal units (NNUs). This research study had aimed to assess the
evidence related to infection anticipation strategy for CVCs as suggested under the national
guidelines and relate the prevention strategy for decreasing the threat of central venous
catheters (CVC)-associated contamination in neonatal units.