Plasma Rich Protein and its Effects on Wound Healing - Nursing Assignment

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NURSING ASSIGNMENT
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NURSING ASSIGNMENT1
Plasma rich protein and its effects wound healing
Wound care practitioners are often asked to provide care that are a bit different from the
mainstream wound care facilities. This report will provide a description of the effect of platelet
rich plasma in wound healing.
Autologous platelet rich plasma (PRP) has been considered to be an advanced wound
therapy against some acute wounds that are hard to heal (Kim et al.,2017). Platelet –rich plasma
(PRP) is an endogenous therapeutic technique, that is receiving interest in the degenerative
medicine due to its capacity to stimulate and speed up the recovery of the wound. Platelets plays
an important role in the wound healing (Chicharro-Alcántara et al., 2016).
PRP gel contains chemokines, growth factors and cytokines and fibrin scaffold that has
been derived from blood of a patient. Apart from this, there are several other growth factors like
platelet –derived growth factors (PDGF), epidermal growth factors (EGF) fibroblast growth
factors (FGF). The mechanism of action of the PRP gel has been estimated to be the induction
of the wound in the molecular and the cellular level, similar to the activation of the platelet.
Evaluation of the PRP gel has been done in several studies (Chicharro-Alcántara et al., 2016).
One of the systematic review has looked upon the regeneration of the tissue in the maxillofacial
surgery, chronic ulcers and the surgical wounds. There had been randomized controlled trials
that have shown statistically significant differences in the reduction of the wound area in
comparison to saline gauze .Again a study has found that wound closure has been found to be
faster in the PRP applied wounds in comparison to Bacitracin (Dhurat & Sukesh, 2014). Pain
scores in the PRP treated wound has again been found to be less than that of the saline gauze,
saline gel or topical treatment.