1 NURSING Answer 1 The random capillary blood glucose level (BGL) of Sarah was 25.0 mmol/L and in emergency department it was 1.6 mmol/L. According toKleinridders, Ferris, Cai and Kahn (2014)children who are over 2 years of the age the normal BGL is 6.1 mmol/L (measured at any point of time with no regard of food intake). Sarah has been prescribed to take insulin because Sarah is suffering from type 1 diabetes. Under this condition, the isletofLangerhans inthepancreas failstoproduce required insulin in order to manage the blood glucose. The externally injected insulin helps to reduce the blood glucose level by signalling the liver and the muscle cells to take up glucose from the blood. The insulin injected subcutaneously (fat layer betweenskinandmuscles)promotesslowabsorptionofinsulininbloodand promoting longer action of insulin. The subcutaneous injection is also less painful. The injection of Novorapid insulin further increases the half life of insulin as it is long- acting analogue of insulin(Iqbal, Novodvorsky & Heller, 2018). Answer 2 a. The onset of action of NovoRapid insulin occurs within 10 to 20 minutes after the subcutaneous administration. The peak action of insulin is exerted within 1 to 3 hours post the time of injection. The total duration of action of NovoRapid once administered within the body is 3 to 5 hours (Galbraith, Bullock & Manias, 2017). b. NovoRapid has faster degree of onset and shorter duration of action in compariosn to the soluble insulin produced in human body. It is 30 times faster in compariosn to the biphasic human insulin. Due to its faster onset of action, the NovoRapid insulin is administered immediately before the intake of meal or when
2 NURSING necessary like immediately after the intake of meal (Galbraith, Bullock & Manias, 2017). Answer 3 a. Hypoglycemia is defined as a condition where the blood glucose level falls below normal (International Hypoglycaemia Study Group, 2015). b. In case of patients suffering from type 1 diabetes mellitus, hypoglycemia canoccurwhenthepatientisundersubcutaneousinsulininjectionandalso performs high intensity physical activity simultaneously. Like in case of Sarah, intake of NovoRapid (three times per day) along with taking swimming lessons and dance classes might lead to generation of hypoglycemia. Insulin over-dose in glycemic patients can also cause diabetes (International Hypoglycaemia Study Group, 2015). c. The main symptoms of hypoglycemia include shakiness, dizziness, profuse sweating, nervousness, anxiety and in extreme cases, it might lead to numbness of handandfeet,suddendropinbodytemperatureandlossofconsciousness (International Hypoglycaemia Study Group, 2015). d. The immediate and best treatment for hypoglcemia include consumption of at least 15 to 20 grams of fast action carbohydrate like sugar or fruit juice in order to restore the glucose balance in body (International Hypoglycaemia Study Group, 2015). Answer 4 a. Bergenstal et al. (2015) stated that shorter needles ensure lower degree of pain upon injection. The length of the needle varies with age and the dosage of
3 NURSING injection. In case of child like Sarah, the distance from the skin and the fat tissue or subcutaneous tissue is less and thus the length of the pen needle must be no longer than 4 mm (Bergenstal et al., 2015). b.Thislengthisappropriatebecause,theshortlengthwillpreventthe penetration of the needle into the muscle cells and thus ensuring slow release of the insulin and lesser pain (Bergenstal et al., 2015). c. The dosage of Sarah is less that is 3 units thrice per day and Sarah goes to Kindergarten. Depending on the dosage and age, this needle length is best suited for her (Bergenstal et al., 2015). Answer 6 a. There are four different areas in a child’s body, which is suitable for insulin injection. These areas include thighs, abdomen, backside of the upper arms and upper outer buttocks. It is recommended to rotate the site of insulin injection in order to reduce the severity of pain (Frid et al., 2016). b. The angle for insulin injection is 45 degree as Sarah is a child and creation of bolus is important. However, if the needle size is short that is 4 mm then the angle must be 90 degree in order to ensure that the insulin enters directly into the subcutaneous layer (that is just below the skin) (Frid et al., 2016). c. There areas are suitable for injecting insulin for Sarah because the upper part of skin in these areas are thick and thus helping to prevent the penetration of the needle into the muscle cells (Frid et al., 2016).
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4 NURSING Answer 7 a. The BGL level of Sarah must be tested after administration of NovoRapid because it will help to check the decrease of the BGL upon the action of insulin and will help to reduce the chances of hypoglycemia (American Diabetes Association, 2015). b. The drop in the blood glucose level will help to determine the dosage adjustment. For example if administration of 3 units of NovoRapid fails to decrease the BGL of Sarah then dosage will be increase. On the other hand, if this dosage decreases the BGL below the normal (hypoglycemia) then immediate intake of sugar willbefollowedbydecreaseintheprescribeddosage(AmericanDiabetes Association, 2015). Answer 8 The children like Sarah who have early onset of type 1 diabetes along with a prolongtenureofhyperglycemiasuffersfromcognitiveimpairmentalongwith decrease in the gray matter volume in comparison to the healthy children. This leads hamper the process of overall development. Sarah might face learning difficulties alongwithprobleminconcentratingwhilestudyingwhileinschool.Other physiological challenges include constant feeling of fatigue or nausea (Streisand & Monaghan, 2014). Answer 9 Type 1diabetes has causedSarahtoreducedrastic weight alongwith frequent urge of urinating. The doctor has prescribed for diabetes service for ongoing care along with subcutaneous insulin injection. This might make Sarah feel isolated
5 NURSING of different from rest of his friend and thus increasing the feeling of depression. A sense of denial might also arise. This means denial from the fact that she has to take medicationsandthuscreatinganincreasedsenseofanger,frustrationand resentment (Delamater et al., 2014).
6 NURSING References American Diabetes Association (2015). Standards of medical care in diabetes—2015 abridged for primary care providers.Clinical diabetes: a publication of the American Diabetes Association,33(2), 97. doi:10.2337/diaclin.33.2.97 Bergenstal, R. M., Strock, E. S., Peremislov, D., Gibney, M. A., Parvu, V., & Hirsch, L. J. (2015, March). Safety and efficacy of insulin therapy delivered via a 4mm pen needle in obese patients with diabetes. InMayo Clinic Proceedings(Vol. 90,No.3,pp.329-338).Elsevier. https://doi.org/10.1016/j.mayocp.2014.12.014 Delamater, A. M., de Wit, M., McDarby, V., Malik, J., & Acerini, C. L. (2014). Psychological care of children and adolescents with type 1 diabetes.Pediatric diabetes,15(S20), 232-244.https://doi.org/10.1111/pedi.12191 Frid, A. H., Kreugel, G., Grassi, G., Halimi, S., Hicks, D., Hirsch, L. J., ... & Kalra, S. (2016, September). New insulin delivery recommendations. InMayo Clinic Proceedings(Vol.91,No.9,pp.1231-1255).Elsevier. https://doi.org/10.1016/j.mayocp.2016.06.010 Galbraith, A., Bullock, S., & Manias, E. (2017).Fundamentals of pharmacology: A text for nurses and allied health professionals. Pearson Education Australia. InternationalHypoglycaemiaStudyGroup.(2015).Minimizinghypoglycemiain diabetes.Diabetes Care,38(8), 1583-1591.https://doi.org/10.2337/dc15-0279
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7 NURSING Iqbal, A., Novodvorsky, P., & Heller, S. R. (2018). Recent updates on type 1 diabetes mellitus management for clinicians.Diabetes & metabolism journal,42(1), 3- 18.https://doi.org/10.4093/dmj.2018.42.1.3 Kleinridders, A., Ferris, H. A., Cai, W., & Kahn, C. R. (2014). Insulin action in brain regulatessystemicmetabolismandbrainfunction.Diabetes,63(7),2232- 2243.https://doi.org/10.2337/db14-0568 Streisand,R.,&Monaghan,M.(2014).Youngchildrenwithtype1diabetes: challenges, research, and future directions.Current diabetes reports,14(9), 520. doi:10.1007/s11892-014-0520-2