Exploring Organ-on-Chips Technology: Advancements, Features, and Applications

Organ-on-chips technology

ORGAN-ON-CHIPS TECHNOLOGY
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Organ-on-chips technology
The organ on the chip is defined as a technology that offers an alternative animal
testing process where each individual chip is composed of a clear flexible polymer about
the size of a computer memory stick (Elveflow, 2018). It is the multi-channel 3D
microfluidic cell chip which simulates the activities and physiological response of the
complete organs. The aim of this essay is to understand the concept of the organ on chip
technology with their features. This essay will describe the phenomena of the organ oh
a chip with their working principle and advantages and disadvantages of this
technology.
Organs on the chip are an advanced technology which is developed on the micro-
contrived chips that size is around AA battery. It has the ability to assist researchers to
gain a well sympathetic of the impact of the drugs, infection bacteria in nutrients and
additional damaging materials on the consumer body system (Emulate bio, 2016).
There are major 3 mechanisms of this technology, for example, organ chips, software
applications, and instrumentation. The organ chips are developed to re-form the usual
makeup and motorized forces which cell experiences in the individual’s body system.
These chips are linked with the individual’s cells and their tiny fluidic channels produce
the blood in the consumer body system. In which the size of each organ chip is around
AA battery and they are more flexible to recreate the breathing motions.
The instrumentations are developed for recreating the consumer body’s living
process which involves the flow of blood and breathing movement. In several cases, the
organ chips are connected with each other so that researcher can observe how the
various organ systems interact with each other (FDA, 2018). During the software
application process, the researcher can extract data and information which can be
gathered and analyzed by using modern software. Such kind of software is developed to
provide the precise control and monitor of the organ system's living microenvironment.
It is observed that the software application has the capability to configure cell networks
and architecture, mechanical forces, and biochemical surroundings.
There are many advantages of this technology such as speeding up research,
more accurate and flexible rather than other, it is very easy to understand and use,