This assignment delves into the crucial role of peroxisome proliferators (PPARs) in regulating metabolic processes. It outlines the three main subtypes – PPARα, PPARδ, and PPARγ – and their distinct expression patterns and functions. The text emphasizes how PPARs are activated by ligands like fatty acids and thiazolidinediones, influencing glucose and lipid metabolism, energy balance, and gene expression. It further discusses the implications of PPARs in conditions such as type II diabetes, obesity, metabolic syndromes, and dyslipidemia.